Tissue factor

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Current revision (10:08, 26 February 2020) (edit) (undo)
 
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*Tissue factor
*Tissue factor
-
**[[1a21]] – rTF extracellular domain – rabbit<br />
 
**[[2hft]], [[1boy]], [[1tfh]] – hTF extracellular domain – human<br />
**[[2hft]], [[1boy]], [[1tfh]] – hTF extracellular domain – human<br />
 +
**[[1a21]] – rTF extracellular domain – rabbit<br />
*Tissue factor binary complex
*Tissue factor binary complex
-
**[[1dan]], [[1j9c]], [[1w0y]], [[4ylq]], [[4z6a]], [[4zma]] – hTF extracellular domain + factor VIIA<br />
+
**[[1dan]], [[1j9c]], [[1w0y]], [[4ylq]], [[4z6a]], [[4zma]], [[6r2w]] – hTF extracellular domain + factor VIIA<br />
**[[1o5d]] – hTF extracellular domain (mutant) + factor VIIA<br />
**[[1o5d]] – hTF extracellular domain (mutant) + factor VIIA<br />
**[[1ahw]], [[1jps]], [[1uj3]], [[4m7l]], [[5w06]] – hTF extracellular domain + antibody<br />
**[[1ahw]], [[1jps]], [[1uj3]], [[4m7l]], [[5w06]] – hTF extracellular domain + antibody<br />

Current revision

Structure of human tissue factor (green) complex with coagulation factor VIIa heavy chain (magenta) and light chain (deep sky blue) and Ca+2 ion (green) (PDB code 1j9c).

Drag the structure with the mouse to rotate

3D structures of tissue factor

Updated on 26-February-2020

References

  1. ↑ Chen VM, Hogg PJ. Encryption and decryption of tissue factor. J Thromb Haemost. 2013 Jun;11 Suppl 1:277-84. doi: 10.1111/jth.12228. PMID:23809131 doi:http://dx.doi.org/10.1111/jth.12228
  2. ↑ Poon RT, Lau CP, Ho JW, Yu WC, Fan ST, Wong J. Tissue factor expression correlates with tumor angiogenesis and invasiveness in human hepatocellular carcinoma. Clin Cancer Res. 2003 Nov 1;9(14):5339-45. PMID:14614019
  3. ↑ Pawlinski R, Tencati M, Holscher T, Pedersen B, Voet T, Tilley RE, Marynen P, Mackman N. Role of cardiac myocyte tissue factor in heart hemostasis. J Thromb Haemost. 2007 Aug;5(8):1693-700. PMID:17663739 doi:http://dx.doi.org/10.1111/j.1538-7836.2007.02649.x

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky

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