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Sandbox GGC4

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==Name of your molecule==
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==Pax6 paired domain protein==
<StructureSection load='6PAX' size='340' side='right' caption='Caption for this structure' scene='75/752268/Full_protein_dna_hidden_orient/1'>
<StructureSection load='6PAX' size='340' side='right' caption='Caption for this structure' scene='75/752268/Full_protein_dna_hidden_orient/1'>
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This is a default text for your page '''Sandbox GGC4'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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Pax6 is a transcription factor necessary for the development of the eye, parts of the central nervous system,and crucial parts of the endocrine system including the pituitary gland, pineal gland, and pancreas <ref>PMID:27771509</ref>.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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<ref>PMID:10346815</ref>
== Function ==
== Function ==

Revision as of 14:00, 2 October 2019

Pax6 paired domain protein

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. ↑ Wang X, Shan X, Gregory-Evans CY. A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):60-67. doi:, 10.1016/j.bbadis.2016.10.018. Epub 2016 Oct 20. PMID:27771509 doi:http://dx.doi.org/10.1016/j.bbadis.2016.10.018
  2. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  3. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  4. ↑ Xu HE, Rould MA, Xu W, Epstein JA, Maas RL, Pabo CO. Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes Dev. 1999 May 15;13(10):1263-75. PMID:10346815
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