6kr3

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'''Unreleased structure'''
 
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The entry 6kr3 is ON HOLD until Paper Publication
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==Crystal structure of Dengue virus nonstructural protein NS5 (form 2)==
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<StructureSection load='6kr3' size='340' side='right'caption='[[6kr3]], [[Resolution|resolution]] 2.93&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6kr3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KR3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KR3 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kr3 OCA], [http://pdbe.org/6kr3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kr3 RCSB], [http://www.ebi.ac.uk/pdbsum/6kr3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kr3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q91H74_9FLAV Q91H74_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Gong, P]]
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[[Category: Lu, G]]
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[[Category: Wu, J]]
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[[Category: Ye, H Q]]
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[[Category: Methyltransferase]]
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[[Category: Polymerase]]
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[[Category: Viral protein]]

Revision as of 09:07, 1 April 2020

Crystal structure of Dengue virus nonstructural protein NS5 (form 2)

PDB ID 6kr3

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