6su0
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of dimethylated RSLex in complex with cucurbit[7]uril== | |
| + | <StructureSection load='6su0' size='340' side='right'caption='[[6su0]], [[Resolution|resolution]] 1.98Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6su0]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SU0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SU0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MFU:ALPHA-L-METHYL-FUCOSE'>MFU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=QQ7:CUCURBIT[7]URIL'>QQ7</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6su0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6su0 OCA], [http://pdbe.org/6su0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6su0 RCSB], [http://www.ebi.ac.uk/pdbsum/6su0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6su0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | A crystalline biohybrid with a 4 : 1 protein : cucurbituril mass ratio is presented. This result was achieved by engineering additional cucurbit[7]uril (Q7) binding sites into a beta-propeller protein. In contrast to the parent protein, Q7-controlled assembly of the engineered variant occurred in solution, as evidenced by NMR and SAXS measurements. | ||
| - | + | Engineered assembly of a protein-cucurbituril biohybrid.,Guagnini F, Engilberge S, Ramberg KO, Perez J, Crowley PB Chem Commun (Camb). 2020 Jan 2;56(3):360-363. doi: 10.1039/c9cc07198a. PMID:31825399<ref>PMID:31825399</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Crowley, P | + | <div class="pdbe-citations 6su0" style="background-color:#fffaf0;"></div> |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Crowley, P B]] | ||
[[Category: Engilberge, S]] | [[Category: Engilberge, S]] | ||
| + | [[Category: Guagnini, F]] | ||
| + | [[Category: Crystal engineering]] | ||
| + | [[Category: Cucurbituril]] | ||
| + | [[Category: Molecular glue]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 06:34, 19 February 2020
Crystal structure of dimethylated RSLex in complex with cucurbit[7]uril
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