6u3p
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Binary complex of native hAChE with oxime reactivator LG-703== | |
| - | + | <StructureSection load='6u3p' size='340' side='right'caption='[[6u3p]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6u3p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U3P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6U3P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PQY:(2E,2E)-N,N-[1,4-diazepane-1,4-diyldi(ethane-2,1-diyl)]bis[2-(hydroxyimino)acetamide]'>PQY</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6u3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u3p OCA], [http://pdbe.org/6u3p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6u3p RCSB], [http://www.ebi.ac.uk/pdbsum/6u3p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6u3p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACES_HUMAN ACES_HUMAN]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.<ref>PMID:2714437</ref> <ref>PMID:1748670</ref> <ref>PMID:1517212</ref> <ref>PMID:11985878</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Acetylcholinesterase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Gerlits, O]] | [[Category: Gerlits, O]] | ||
| + | [[Category: Kovalevsky, A]] | ||
[[Category: Radic, Z]] | [[Category: Radic, Z]] | ||
| - | [[Category: | + | [[Category: Bis-oxime]] |
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Reactivator complex]] | ||
Revision as of 04:28, 13 February 2020
Binary complex of native hAChE with oxime reactivator LG-703
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