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Sandbox GGC4
From Proteopedia
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==Pax6 paired domain protein== | ==Pax6 paired domain protein== | ||
| - | <StructureSection load='6PAX' size='340' side='right' caption='Caption for this structure' scene='75/752268/Full_protein_dna_hidden_orient/ | + | <StructureSection load='6PAX' size='340' side='right' caption='Caption for this structure' scene='75/752268/Full_protein_dna_hidden_orient/3'> |
Pax6 is a transcription factor necessary for the development of the eye, parts of the central nervous system,and crucial parts of the endocrine system including the pituitary gland, pineal gland, and pancreas <ref>PMID:27771509</ref>. | Pax6 is a transcription factor necessary for the development of the eye, parts of the central nervous system,and crucial parts of the endocrine system including the pituitary gland, pineal gland, and pancreas <ref>PMID:27771509</ref>. | ||
Revision as of 14:05, 2 October 2019
Pax6 paired domain protein
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References
- ↑ Wang X, Shan X, Gregory-Evans CY. A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):60-67. doi:, 10.1016/j.bbadis.2016.10.018. Epub 2016 Oct 20. PMID:27771509 doi:http://dx.doi.org/10.1016/j.bbadis.2016.10.018
- ↑ Xu HE, Rould MA, Xu W, Epstein JA, Maas RL, Pabo CO. Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes Dev. 1999 May 15;13(10):1263-75. PMID:10346815
