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2bkq

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<StructureSection load='2bkq' size='340' side='right'caption='[[2bkq]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2bkq' size='340' side='right'caption='[[2bkq]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bkq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BKQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bkq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BKQ FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xt9|1xt9]], [[2bkr|2bkr]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xt9|1xt9]], [[2bkr|2bkr]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bkq OCA], [http://pdbe.org/2bkq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bkq RCSB], [http://www.ebi.ac.uk/pdbsum/2bkq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bkq ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bkq OCA], [https://pdbe.org/2bkq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bkq RCSB], [https://www.ebi.ac.uk/pdbsum/2bkq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bkq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SENP8_HUMAN SENP8_HUMAN]] Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.<ref>PMID:12730221</ref> <ref>PMID:12759363</ref> <ref>PMID:12759362</ref> <ref>PMID:15242646</ref> <ref>PMID:15775960</ref>
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[[https://www.uniprot.org/uniprot/SENP8_HUMAN SENP8_HUMAN]] Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.<ref>PMID:12730221</ref> <ref>PMID:12759363</ref> <ref>PMID:12759362</ref> <ref>PMID:15242646</ref> <ref>PMID:15775960</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 13:38, 13 October 2021

NEDD8 protease

PDB ID 2bkq

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