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1cit

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<StructureSection load='1cit' size='340' side='right'caption='[[1cit]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='1cit' size='340' side='right'caption='[[1cit]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1cit]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CIT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1cit]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CIT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cit OCA], [http://pdbe.org/1cit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1cit RCSB], [http://www.ebi.ac.uk/pdbsum/1cit PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1cit ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cit OCA], [https://pdbe.org/1cit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cit RCSB], [https://www.ebi.ac.uk/pdbsum/1cit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cit ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NR4A1_RAT NR4A1_RAT]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2 (By similarity).
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[[https://www.uniprot.org/uniprot/NR4A1_RAT NR4A1_RAT]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2 (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 10:37, 14 July 2021

DNA-BINDING MECHANISM OF THE MONOMERIC ORPHAN NUCLEAR RECEPTOR NGFI-B

PDB ID 1cit

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