Siderocalin

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Line 16: Line 16:
*Siderocalin or lipocalin-2
*Siderocalin or lipocalin-2
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**[[5jr8]], [[3bx8]], [[5khp]], [[5kid]], [[5kic]], [[5mhh]], [[6gqz]] – hScn NGAL - human<br />
+
**[[5jr8]], [[3bx8]], [[5khp]], [[5kid]], [[5kic]], [[5mhh]], [[6gqz]], [[1qqs]] – hScn NGAL - human<br />
 +
**[[1l6m]], [[3dtq]], [[4iaw]], [[4iax]], [[6qmu]] – hScn NGAL (mutant)<br />
**[[3s26]] – mScn NGAL - mouse<br />
**[[3s26]] – mScn NGAL - mouse<br />
 +
**[[2k23]] – Scn NGAL – rat - NMR<br />
**[[2kt4]] – qScn Q83 – quail<br />
**[[2kt4]] – qScn Q83 – quail<br />

Revision as of 10:07, 5 February 2020

Human siderocalin complex with the siderophore carboxymycobactin (PDB code 1x89)

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3D structures of siderocalin

Updated on 05-February-2020

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References

  1. Hoette TM, Abergel RJ, Xu J, Strong RK, Raymond KN. The role of electrostatics in siderophore recognition by the immunoprotein Siderocalin. J Am Chem Soc. 2008 Dec 24;130(51):17584-92. doi: 10.1021/ja8074665. PMID:19053425 doi:http://dx.doi.org/10.1021/ja8074665
  2. Paragas N, Qiu A, Hollmen M, Nickolas TL, Devarajan P, Barasch J. NGAL-Siderocalin in kidney disease. Biochim Biophys Acta. 2012 Sep;1823(9):1451-8. doi: 10.1016/j.bbamcr.2012.06.014., Epub 2012 Jun 19. PMID:22728330 doi:http://dx.doi.org/10.1016/j.bbamcr.2012.06.014
  3. Holmes MA, Paulsene W, Jide X, Ratledge C, Strong RK. Siderocalin (Lcn 2) also binds carboxymycobactins, potentially defending against mycobacterial infections through iron sequestration. Structure. 2005 Jan;13(1):29-41. PMID:15642259 doi:10.1016/j.str.2004.10.009

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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