Carboxypeptidase 3D structures
From Proteopedia
(Difference between revisions)
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*'''Carboxypeptidase A''' | *'''Carboxypeptidase A''' | ||
| + | **[[2v77]] – hCPA1 – human<br /> | ||
**[[5cpa]], [[1yme]], [[1cps]], [[1ee3]], [[1cpx]], [[1m4l]] – bCPA – bovine<br /> | **[[5cpa]], [[1yme]], [[1cps]], [[1ee3]], [[1cpx]], [[1m4l]] – bCPA – bovine<br /> | ||
**[[1arl]] – bCPA <br /> | **[[1arl]] – bCPA <br /> | ||
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**[[1ka2]], [[1ka4]] - PfCPA Zn-substituted<br /> | **[[1ka2]], [[1ka4]] - PfCPA Zn-substituted<br /> | ||
**[[5wvu]], [[3hoa]] – CPA – ''Thermus thermophilus''<br /> | **[[5wvu]], [[3hoa]] – CPA – ''Thermus thermophilus''<br /> | ||
| - | **[[2v77]] – hCPA1 – human<br /> | ||
**[[3dwc]] – CPA – ''Trypanosoma cruzi''<br /> | **[[3dwc]] – CPA – ''Trypanosoma cruzi''<br /> | ||
**[[3g23]] – CPA – ''Novosphingobium aromaticivorans''<br /> | **[[3g23]] – CPA – ''Novosphingobium aromaticivorans''<br /> | ||
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*''CPA complex with small molecules'' | *''CPA complex with small molecules'' | ||
| + | **[[2pcu]] – hCPA4 + peptide <br /> | ||
| + | **[[4uee]], [[4uef]], [[4uez]] – hCPA1 + peptide inhibitor<br /> | ||
| + | **[[4uf4]], [[5om9]], [[6i6z]] – hCPA1 + inhibitor<br /> | ||
**[[3cpa]] – bCPA + glycyl-tyrosine <br /> | **[[3cpa]] – bCPA + glycyl-tyrosine <br /> | ||
**[[1f57]] – bCPA + cysteine<br /> | **[[1f57]] – bCPA + cysteine<br /> | ||
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**[[3i1u]] – bCPA + thiirane<br /> | **[[3i1u]] – bCPA + thiirane<br /> | ||
**[[2ctb]], [[2ctc]] – bCPA + phenyl lactate<br /> | **[[2ctb]], [[2ctc]] – bCPA + phenyl lactate<br /> | ||
| - | **[[2pcu]] – hCPA4 + peptide <br /> | ||
| - | **[[4uee]], [[4uef]], [[4uez]] – hCPA1 + peptide inhibitor<br /> | ||
| - | **[[4uf4]], [[5om9]], [[6i6z]] – hCPA1 + inhibitor<br /> | ||
**[[4oxd]] – SpCP + peptidoglycan<br /> | **[[4oxd]] – SpCP + peptidoglycan<br /> | ||
*''CPA complex with protein'' | *''CPA complex with protein'' | ||
| - | **[[1zlh]] – bCPA + tick inhibitor<br /> | ||
| - | **[[4cpa]] – bCPA + potato inhibitor<br /> | ||
| - | **[[2abz]] - bCPA + metallo-CP inhibitor<br /> | ||
**[[3fju]] – hCPA1 + ascaris inhibitor<br /> | **[[3fju]] – hCPA1 + ascaris inhibitor<br /> | ||
**[[1dtd]] – hCPA2 + metallo-CP inhibitor<br /> | **[[1dtd]] – hCPA2 + metallo-CP inhibitor<br /> | ||
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**[[4bd9]] - hCPA4 hydrolase domain + SMCI inhibitor<br /> | **[[4bd9]] - hCPA4 hydrolase domain + SMCI inhibitor<br /> | ||
**[[4a94]] – hCPA4 + nerita versicolor inhibitor<br /> | **[[4a94]] – hCPA4 + nerita versicolor inhibitor<br /> | ||
| + | **[[1zlh]] – bCPA + tick inhibitor<br /> | ||
| + | **[[4cpa]] – bCPA + potato inhibitor<br /> | ||
| + | **[[2abz]] - bCPA + metallo-CP inhibitor<br /> | ||
*'''Procarboxypeptidase A''' | *'''Procarboxypeptidase A''' | ||
| + | **[[1aye]] – hPCPA2 <br /> | ||
| + | **[[1o6x]] – hPCPA2 activation domain – NMR<BR /> | ||
| + | **[[2boa]] – hPCPA4<br /> | ||
**[[1fon]] – bPCPA subunit III<br /> | **[[1fon]] – bPCPA subunit III<br /> | ||
**[[1pyt]] – bPCPA + proproteinase E + chymotrypsinogen C<br /> | **[[1pyt]] – bPCPA + proproteinase E + chymotrypsinogen C<br /> | ||
**[[1jqg]] – PCPA – Cotton bollworm<br /> | **[[1jqg]] – PCPA – Cotton bollworm<br /> | ||
| - | **[[1aye]] – hPCPA2 <br /> | ||
| - | **[[1o6x]] – hPCPA2 activation domain – NMR<BR /> | ||
| - | **[[2boa]] – hPCPA4<br /> | ||
*'''Carboxypeptidase B''' | *'''Carboxypeptidase B''' | ||
| - | **[[1cpb]], [[3dgv]] – bCPB <br /> | ||
| - | **[[3d4u]], [[3osl]] – bCPB + CP inhibitor<br /> | ||
| - | **[[2c1c]] – CPB – Corn earworm<br /> | ||
| - | **[[3glj]] – pCPB residues 16-416 - pig<br /> | ||
| - | **[[5jc6]] – pCPB catalytic domain residues 111-416 <br /> | ||
| - | **[[3wab]], [[3wc5]], [[3wc6]], [[3wc7]], [[5lyf]], [[5lyi]], [[5lyl]], [[4z65]], [[4uia]], [[2piy]], [[2piz]], [[2pj0]], [[2pj1]], [[2pj2]], [[2pj3]], [[2pj4]], [[2pj5]], [[2pj6]], [[2pj7]], [[2pj8]], [[2pj9]], [[2pja]], [[2pjb]], [[2pjc]], [[5j1q]], [[5zeq]] – pCPB catalytic domain + inhibitor<br /> | ||
| - | **[[5lyd]], [[4uib]] – pCPB catalytic domain (mutant) + inhibitor<br /> | ||
| - | **[[5lrg]], [[5lrj]], [[5lrk]] – pCPB catalytic domain + anabaenopepsin peptide<br /> | ||
**[[3d66]] – hCPB 2<br /> | **[[3d66]] – hCPB 2<br /> | ||
**[[3d68]] – hCPB 2 (mutant)<br /> | **[[3d68]] – hCPB 2 (mutant)<br /> | ||
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**[[3d67]] – hCPB 2 + GEMSA<br /> | **[[3d67]] – hCPB 2 + GEMSA<br /> | ||
**[[1zli]] - hCPB + tick inhibitor<br /> | **[[1zli]] - hCPB + tick inhibitor<br /> | ||
| + | **[[1cpb]], [[3dgv]] – bCPB <br /> | ||
| + | **[[3d4u]], [[3osl]] – bCPB + CP inhibitor<br /> | ||
| + | **[[3glj]] – pCPB residues 16-416 - pig<br /> | ||
| + | **[[5jc6]] – pCPB catalytic domain residues 111-416 <br /> | ||
| + | **[[3wab]], [[3wc5]], [[3wc6]], [[3wc7]], [[5lyf]], [[5lyi]], [[5lyl]], [[4z65]], [[4uia]], [[2piy]], [[2piz]], [[2pj0]], [[2pj1]], [[2pj2]], [[2pj3]], [[2pj4]], [[2pj5]], [[2pj6]], [[2pj7]], [[2pj8]], [[2pj9]], [[2pja]], [[2pjb]], [[2pjc]], [[5j1q]], [[5zeq]] – pCPB catalytic domain + inhibitor<br /> | ||
| + | **[[5lyd]], [[4uib]] – pCPB catalytic domain (mutant) + inhibitor<br /> | ||
| + | **[[5lrg]], [[5lrj]], [[5lrk]] – pCPB catalytic domain + anabaenopepsin peptide<br /> | ||
| + | **[[2c1c]] – CPB – Corn earworm<br /> | ||
*'''Procarboxypeptidase B''' | *'''Procarboxypeptidase B''' | ||
| + | **[[1kwm]] - hPCPB<br /> | ||
**[[1pba]] – pPCPB activation domain – NMR<BR /> | **[[1pba]] – pPCPB activation domain – NMR<BR /> | ||
**[[1nsa]] – pPCPB<br /> | **[[1nsa]] – pPCPB<br /> | ||
**[[1z5r]] - pPCPB catalytic domain<br /> | **[[1z5r]] - pPCPB catalytic domain<br /> | ||
| - | **[[1kwm]] - hPCPB<br /> | ||
**[[1pca]] – pPCPB + valine<br /> | **[[1pca]] – pPCPB + valine<br /> | ||
**[[1zg7]], [[1zg8]], [[1zg9]] – pPCPB + inhibitor<br /> | **[[1zg7]], [[1zg8]], [[1zg9]] – pPCPB + inhibitor<br /> | ||
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*'''Carboxypeptidase D''' | *'''Carboxypeptidase D''' | ||
| + | **[[5aq0]] – hCPD transthyretin-like domain<br /> | ||
**[[1qmu]] – dCPD domain II - duck <br /> | **[[1qmu]] – dCPD domain II - duck <br /> | ||
**[[1h8l]] - dCPD domain II + GEMSA<br /> | **[[1h8l]] - dCPD domain II + GEMSA<br /> | ||
**[[3mn8]] – DmCPD + GEMSA – ''Drosophila melanogaster''<br /> | **[[3mn8]] – DmCPD + GEMSA – ''Drosophila melanogaster''<br /> | ||
| - | **[[5aq0]] – hCPD transthyretin-like domain<br /> | ||
*'''Dipeptidyl carboxypeptidase I''' | *'''Dipeptidyl carboxypeptidase I''' | ||
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*''Dipeptidyl carboxypeptidase I complexes'' | *''Dipeptidyl carboxypeptidase I complexes'' | ||
| - | **[[2x8z]], [[2x90]], [[2x91]], [[2x92]], [[2x93]], [[2x94]], [[2x95]], [[2x96]], [[2x97]] – DmCPI + anti-hypersensitive drug<br /> | ||
| - | **[[2xhm]] - DmCPI + phosphate derivative<br /> | ||
**[[2oc2]], [[2xy9]], [[2xyd]] – hCPI + phosphate derivative<br /> | **[[2oc2]], [[2xy9]], [[2xyd]] – hCPI + phosphate derivative<br /> | ||
**[[3nxq]] - hCPI (mutant) + phosphate derivative<br /> | **[[3nxq]] - hCPI (mutant) + phosphate derivative<br /> | ||
**[[3bkk]], [[3bkl]], [[3l3n]] – hCPI + inhibitor<br /> | **[[3bkk]], [[3bkl]], [[3l3n]] – hCPI + inhibitor<br /> | ||
**[[2ydm]], [[3zqz]] – hCPI + captopril derivative<br /> | **[[2ydm]], [[3zqz]] – hCPI + captopril derivative<br /> | ||
| + | **[[2x8z]], [[2x90]], [[2x91]], [[2x92]], [[2x93]], [[2x94]], [[2x95]], [[2x96]], [[2x97]] – DmCPI + anti-hypersensitive drug<br /> | ||
| + | **[[2xhm]] - DmCPI + phosphate derivative<br /> | ||
**[[5l44]] – AhCPI + peptide inhibitor <br /> | **[[5l44]] – AhCPI + peptide inhibitor <br /> | ||
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**[[1obr]], [[3qnv]] – TvCPT – ''Thermoaclinomyces vulgaris''<br /> | **[[1obr]], [[3qnv]] – TvCPT – ''Thermoaclinomyces vulgaris''<br /> | ||
**[[3prt]], [[3v38]], [[4ihm]] – TvCPT (mutant)<br /> | **[[3prt]], [[3v38]], [[4ihm]] – TvCPT (mutant)<br /> | ||
| - | **[[4djl]], [[6sn6]], [[6go2]] – TvCPT + sulfamoyl derivative<br /> | + | **[[4djl]], [[6sn6]], [[6go2]], [[6t9y]], [[6tnk]] – TvCPT + sulfamoyl derivative<br /> |
| - | **[[4iav]], [[6q4l]], [[6f79]], [[6f75]], [[6f6q]] – TvCPT (mutant) + sulfamoyl derivative<br /> | + | **[[4iav]], [[6q4l]], [[6f79]], [[6f75]], [[6f6q]], [[6z28]] – TvCPT (mutant) + sulfamoyl derivative<br /> |
**[[4duk]] – TvCPT + benzyl succinic acid<br /> | **[[4duk]] – TvCPT + benzyl succinic acid<br /> | ||
**[[4f8z]] – TvCPT + leucine derivative<br /> | **[[4f8z]] – TvCPT + leucine derivative<br /> | ||
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**[[4rye]] – MtAACP <br /> | **[[4rye]] – MtAACP <br /> | ||
**[[5fsr]] – EcAACP <br /> | **[[5fsr]] – EcAACP <br /> | ||
| + | **[[5tr7]] – AACP – ''Vibrio cholerae''<br /> | ||
| + | **[[6osu]] – AACP – ''Francisella tularensis''<br /> | ||
**[[3pte]], [[1skf]] – StAACP – ''Streptomyces''<br /> | **[[3pte]], [[1skf]] – StAACP – ''Streptomyces''<br /> | ||
**[[1es2]], [[1es3]], [[1es4]], [[1es5]], [[1esi]], [[1j9m]] – StAACP (mutant) <br /> | **[[1es2]], [[1es3]], [[1es4]], [[1es5]], [[1esi]], [[1j9m]] – StAACP (mutant) <br /> | ||
| + | **[[1cef]], [[1ceg]], [[1hvb]], [[1pw1]], [[1pw8]], [[1pwc]], [[1pwd]], [[1pwg]] – StAACP + antibiotic<br /> | ||
| + | **[[1ikg]], [[1iki]] – StAACP + peptidoglycan fragment<br /> | ||
| + | **[[1mpl]] - StAACP + phosphonate inhibitor<br /> | ||
| + | **[[1scw]], [[1sde]] - StAACP + cyclic phosphate inhibitor<br /> | ||
| + | **[[1yqs]] - StAACP + sultam inhibitor<br /> | ||
**[[1lbu]] – SaAACP + Zn – ''Streptomyces albus''<br /> | **[[1lbu]] – SaAACP + Zn – ''Streptomyces albus''<br /> | ||
**[[6c39]] – AACP + Zn – ''Staphylococcus aureus''<br /> | **[[6c39]] – AACP + Zn – ''Staphylococcus aureus''<br /> | ||
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**[[5zhw]] – EfAACP + Zn + Ala-Ala<br /> | **[[5zhw]] – EfAACP + Zn + Ala-Ala<br /> | ||
**[[2wke]], [[1w8y]], [[2vgj]], [[2vgk]], [[4ben]] - AcAACP + antibiotic<br /> | **[[2wke]], [[1w8y]], [[2vgj]], [[2vgk]], [[4ben]] - AcAACP + antibiotic<br /> | ||
| - | **[[1cef]], [[1ceg]], [[1hvb]], [[1pw1]], [[1pw8]], [[1pwc]], [[1pwd]], **[[1pwg]] – StAACP + antibiotic<br /> | ||
**[[2xdm]], [[2xk1]], [[2xln]], [[2y4a]], [[2y55]], [[2y59]], [[3zvt]], [[3zvw]], [[4b4x]], [[4b4z]] – AcAACP + boronic acid derivative<br /> | **[[2xdm]], [[2xk1]], [[2xln]], [[2y4a]], [[2y55]], [[2y59]], [[3zvt]], [[3zvw]], [[4b4x]], [[4b4z]] – AcAACP + boronic acid derivative<br /> | ||
| - | **[[1ikg]], [[1iki]] – StAACP + peptidoglycan fragment<br /> | ||
| - | **[[1mpl]] - StAACP + phosphonate inhibitor<br /> | ||
| - | **[[1scw]], [[1sde]] - StAACP + cyclic phosphate inhibitor<br /> | ||
| - | **[[1yqs]] - StAACP + sultam inhibitor<br /> | ||
**[[3zcz]] – AcAACP + inhibitor<br /> | **[[3zcz]] – AcAACP + inhibitor<br /> | ||
**[[5j8x]] – EcAACP + inhibitor<br /> | **[[5j8x]] – EcAACP + inhibitor<br /> | ||
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**[[1z8l]], [[2oot]] – hECP II<br /> | **[[1z8l]], [[2oot]] – hECP II<br /> | ||
| - | **[[2c6c]], [[2jbj]], [[2jbk]], [[2or4]], [[3d7d]], [[3d7f]], [[3d7g]], [[3d7h]], [[3iww]], [[3sjf]], [[4jyw]], [[4jz0]], [[4lqg]], [[5ely]], [[5d29]], [[4x3r]], [[4w9y]], [[6hkz]], [[6hkj]], [[6h7z]], [[6h7y]], [[6f5l]], [[6ety]] – hECP II + inhibitor<br /> | + | **[[2c6c]], [[2jbj]], [[2jbk]], [[2or4]], [[3d7d]], [[3d7f]], [[3d7g]], [[3d7h]], [[3iww]], [[3sjf]], [[4jyw]], [[4jz0]], [[4lqg]], [[5ely]], [[5d29]], [[4x3r]], [[4w9y]], [[6hkz]], [[6hkj]], [[6h7z]], [[6h7y]], [[6f5l]], [[6ety]], [[6rbc]] – hECP II + inhibitor<br /> |
| - | **[[6fe5]], [[6ez9]], [[5of0]] - hECP II (mutant) + inhibitor<br /> | + | **[[6fe5]], [[6ez9]], [[5of0]], [[6s1x]] - hECP II (mutant) + inhibitor<br /> |
**[[4p44]], [[4p45]], [[4p4e]], [[4p4d]], [[4p4f]], [[4p4i]], [[4p4j]], [[4p4b]] – hECP II + phosphoramidate inhibitor<br /> | **[[4p44]], [[4p45]], [[4p4e]], [[4p4d]], [[4p4f]], [[4p4i]], [[4p4j]], [[4p4b]] – hECP II + phosphoramidate inhibitor<br /> | ||
**[[4ngm]], [[4ngn]], [[4ngp]], [[4ngq]], [[4ngr]], [[4ngs]], [[4ngt]], [[4oc0]], [[4oc1]], [[4oc2]], [[4oc3]], [[4oc4]], [[4oc5]], [[4ome]], [[5o5u]], [[5o5t]], [[5o5r]] - hECP II + urea derivative<br /> | **[[4ngm]], [[4ngn]], [[4ngp]], [[4ngq]], [[4ngr]], [[4ngs]], [[4ngt]], [[4oc0]], [[4oc1]], [[4oc2]], [[4oc3]], [[4oc4]], [[4oc5]], [[4ome]], [[5o5u]], [[5o5t]], [[5o5r]] - hECP II + urea derivative<br /> | ||
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**[[2c6p]], [[2pvw]] - hECP II + phosphate derivative<br /> | **[[2c6p]], [[2pvw]] - hECP II + phosphate derivative<br /> | ||
**[[3rbu]] – hECP II + PMPA<br /> | **[[3rbu]] – hECP II + PMPA<br /> | ||
| + | **[[6rti]] – hECP II + aptamer<br /> | ||
**[[3bxm]] – hECP II (mutant) + dipeptide<br /> | **[[3bxm]] – hECP II (mutant) + dipeptide<br /> | ||
**[[3sje]], [[3sjg]], [[3sjx]] - hECP II (mutant) + inhibitor<br /> | **[[3sje]], [[3sjg]], [[3sjx]] - hECP II (mutant) + inhibitor<br /> | ||
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**[[3n2z]] - hPCP | **[[3n2z]] - hPCP | ||
| + | |||
| + | *'''Tubulinyl-Tyr carboxypeptidase''' | ||
| + | |||
| + | **[[6j4u]], [[6j8n]], [[6j91]], [[6j9h]], [[6k81]], [[6ocf]] – hTTCP 1 + vasohibin-binding protein<br /> | ||
| + | **[[6nvq]] – hTTCP 1 (mutant) + vasohibin-binding protein<br /> | ||
| + | **[[6j7b]] – hTTCP 1 + vasohibin-binding protein + tubulinyl-Tyr derivative<br /> | ||
| + | **[[6j8f]] – hTTCP 1 + vasohibin-binding protein + tubulin peptide<br /> | ||
| + | **[[6ocg]] – hTTCP 1 + vasohibin-binding protein + Tyr derivative<br /> | ||
| + | **[[6och]] – hTTCP 1 + vasohibin-binding protein + parthenolide<br /> | ||
| + | **[[6j4o]], [[6j4p]], [[6j4q]], [[6j4s]], [[6j4u]], [[6j8n]], [[6j91]], [[6qby]] – hTTCP 2 + vasohibin-binding protein<br /> | ||
| + | **[[6j4v]] – hTTCP 2 + vasohibin-binding protein + tubulin<br /> | ||
| + | **[[6j8o]] – hTTCP 2 + vasohibin-binding protein + peptide<br /> | ||
| + | **[[6jzc]], [[6jze]] – mTTCP 2 + vasohibin-binding protein - mouse<br /> | ||
| + | **[[6jzd]] – mTTCP 2 + vasohibin-binding protein + peptide<br /> | ||
*'''Angiotensin-converting enzyme-related carboxypeptidase''' | *'''Angiotensin-converting enzyme-related carboxypeptidase''' | ||
Revision as of 06:18, 1 July 2020
3D Structures of Carboxypeptidase
Updated on 01-July-2020
