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6n6k

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Current revision (06:46, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6n6k' size='340' side='right'caption='[[6n6k]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
<StructureSection load='6n6k' size='340' side='right'caption='[[6n6k]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6n6k]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N6K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N6K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6n6k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N6K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6N6K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.418&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">REXO2, SFN, SMFN, CGI-114 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n6k OCA], [http://pdbe.org/6n6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n6k RCSB], [http://www.ebi.ac.uk/pdbsum/6n6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n6k ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6n6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n6k OCA], [https://pdbe.org/6n6k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n6k RCSB], [https://www.ebi.ac.uk/pdbsum/6n6k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n6k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ORN_HUMAN ORN_HUMAN]] 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role in cellular nucleotide recycling.<ref>PMID:23741365</ref>
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[https://www.uniprot.org/uniprot/ORN_HUMAN ORN_HUMAN] 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role in cellular nucleotide recycling.<ref>PMID:23741365</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6n6k" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6n6k" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Exonuclease 3D structures|Exonuclease 3D structures]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lormand, J D]]
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[[Category: Synthetic construct]]
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[[Category: Sondermann, H]]
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[[Category: Lormand JD]]
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[[Category: 3'-5' exoribonuclease]]
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[[Category: Sondermann H]]
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[[Category: Rna binding protein]]
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[[Category: Rna binding protein-rna complex]]
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Current revision

Human REXO2 bound to pAG

PDB ID 6n6k

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