1emr
From Proteopedia
(Difference between revisions)
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<StructureSection load='1emr' size='340' side='right'caption='[[1emr]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='1emr' size='340' side='right'caption='[[1emr]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1emr]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1emr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EMR FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1emr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1emr OCA], [https://pdbe.org/1emr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1emr RCSB], [https://www.ebi.ac.uk/pdbsum/1emr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1emr ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/LIF_HUMAN LIF_HUMAN]] LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 09:39, 21 July 2021
CRYSTAL STRUCTURE OF HUMAN LEUKEMIA INHIBITORY FACTOR (LIF)
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