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1fxz

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Revision as of 11:16, 28 July 2021

CRYSTAL STRUCTURE OF SOYBEAN PROGLYCININ A1AB1B HOMOTRIMER

Structural highlights

1fxz is a 3 chain structure with sequence from Glycine hispida. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GLYG1_SOYBN] Glycinin is the major seed storage protein of soybean.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Soybean glycinin is a member of the 11 S globulin family. The crystal structure of proglycinin was determined by X-ray crystallography at 2.8 A resolution with an R-factor of 0.199 and a free R-factor of 0.250. A trimer molecule was found in an asymmetric unit of crystals. The trimer model contains three A1aB1b subunits and comprises 1128 amino acid residues and 34 water molecules. The constituent protomers of the homo-trimeric protein are arranged around a 3-fold symmetry axis with dimensions of 95 Ax95 Ax40 A. The protomer model is composed of five fragments which correspond roughly to conserved regions based on the sequence alignment of various 11 S globulins. The core of the protomer consists of two jelly-roll beta-barrels and two extended helix domains. This structure of proglycinin is similar to those of canavalin and phaseolin belonging to the 7 S globulin family, strongly supporting the hypothesis that both 7 S and 11 S globulins are derived from a common ancestor. The inter and intra-chain disulfide bonds conserved in the 11 S globulin family are clearly observed. It is found that the face with the inter-chain disulfide bond (IE face) contains more hydrophobic residues than that with the intra-chain disulfide bond. This suggests that a mature hexamer is formed by the interaction between the IE faces after processing.

Crystal structure of soybean proglycinin A1aB1b homotrimer.,Adachi M, Takenaka Y, Gidamis AB, Mikami B, Utsumi S J Mol Biol. 2001 Jan 12;305(2):291-305. PMID:11124907^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Adachi M, Takenaka Y, Gidamis AB, Mikami B, Utsumi S. Crystal structure of soybean proglycinin A1aB1b homotrimer. J Mol Biol. 2001 Jan 12;305(2):291-305. PMID:11124907 doi:10.1006/jmbi.2000.4310

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1fxz"

@@ Line 3: / Line 3: @@
 <StructureSection load='1fxz' size='340' side='right'caption='[[1fxz]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1fxz]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Glycine_hispida Glycine hispida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FXZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FXZ FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1fxz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Glycine_hispida Glycine hispida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FXZ FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fxz OCA], [http://pdbe.org/1fxz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fxz RCSB], [http://www.ebi.ac.uk/pdbsum/1fxz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fxz ProSAT]</span></td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fxz OCA], [https://pdbe.org/1fxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fxz RCSB], [https://www.ebi.ac.uk/pdbsum/1fxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fxz ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/GLYG1_SOYBN GLYG1_SOYBN]] Glycinin is the major seed storage protein of soybean.
+[[https://www.uniprot.org/uniprot/GLYG1_SOYBN GLYG1_SOYBN]] Glycinin is the major seed storage protein of soybean.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]

1fxz

From Proteopedia

Revision as of 11:16, 28 July 2021

CRYSTAL STRUCTURE OF SOYBEAN PROGLYCININ A1AB1B HOMOTRIMER

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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