1fnx
From Proteopedia
(Difference between revisions)
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<StructureSection load='1fnx' size='340' side='right'caption='[[1fnx]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''> | <StructureSection load='1fnx' size='340' side='right'caption='[[1fnx]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1fnx]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1fnx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FNX FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1d8z|1d8z]], [[1d9a|1d9a]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1d8z|1d8z]], [[1d9a|1d9a]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fnx OCA], [https://pdbe.org/1fnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fnx RCSB], [https://www.ebi.ac.uk/pdbsum/1fnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fnx ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ELAV3_MOUSE ELAV3_MOUSE]] Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance.<ref>PMID:9016658</ref> <ref>PMID:10734193</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 11:12, 28 July 2021
SOLUTION STRUCTURE OF THE HUC RBD1-RBD2 COMPLEXED WITH THE AU-RICH ELEMENT
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