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1if0

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Revision as of 04:20, 5 March 2020

PSEUDO-ATOMIC MODEL OF BACTERIOPHAGE HK97 PROCAPSID (PROHEAD II)

1if0, resolution 12.00Å

Structural highlights

1if0 is a 7 chain structure with sequence from Bphk7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Related:	1fh6
Experimental data:	Check to display Experimental Data
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Large-scale conformational changes transform viral precursors into infectious virions. The structure of bacteriophage HK97 capsid, Head-II, was recently solved by crystallography, revealing a catenated cross-linked topology. We have visualized its precursor, Prohead-II, by cryoelectron microscopy and modeled the conformational change by appropriately adapting Head-II. Rigid-body rotations ( approximately 40 degrees) cause switching to an entirely different set of interactions; in addition, two motifs undergo refolding. These changes stabilize the capsid by increasing the surface area buried at interfaces and bringing the cross-link-forming residues, initially approximately 40 angstroms apart, close together. The inner surface of Prohead-II is negatively charged, suggesting that the transition is triggered electrostatically by DNA packaging.

Virus maturation involving large subunit rotations and local refolding.,Conway JF, Wikoff WR, Cheng N, Duda RL, Hendrix RW, Johnson JE, Steven AC Science. 2001 Apr 27;292(5517):744-8. PMID:11326105^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Conway JF, Wikoff WR, Cheng N, Duda RL, Hendrix RW, Johnson JE, Steven AC. Virus maturation involving large subunit rotations and local refolding. Science. 2001 Apr 27;292(5517):744-8. PMID:11326105 doi:10.1126/science.1058069

1 Structural highlights
2 Evolutionary Conservation
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1if0"

@@ Line 1: / Line 1: @@
 ==PSEUDO-ATOMIC MODEL OF BACTERIOPHAGE HK97 PROCAPSID (PROHEAD II)==
-<StructureSection load='1if0' size='340' side='right'caption='[[1if0]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
+<SX load='1if0' size='340' side='right' viewer='molstar' caption='[[1if0]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
 == Structural highlights ==
 <table><tr><td colspan='2'>[[1if0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Bphk7 Bphk7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IF0 FirstGlance]. <br>
@@ Line 29: / Line 29: @@
 <references/>
 __TOC__
-</StructureSection>
+</SX>
 [[Category: Bphk7]]
 [[Category: Large Structures]]

1if0

From Proteopedia

Revision as of 04:20, 5 March 2020

PSEUDO-ATOMIC MODEL OF BACTERIOPHAGE HK97 PROCAPSID (PROHEAD II)

Structural highlights

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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