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1ixx

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<StructureSection load='1ixx' size='340' side='right'caption='[[1ixx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1ixx' size='340' side='right'caption='[[1ixx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ixx]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IXX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IXX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ixx]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IXX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixx OCA], [http://pdbe.org/1ixx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ixx RCSB], [http://www.ebi.ac.uk/pdbsum/1ixx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ixx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixx OCA], [https://pdbe.org/1ixx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ixx RCSB], [https://www.ebi.ac.uk/pdbsum/1ixx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ixx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IXXB_PROFL IXXB_PROFL]] When linked to subunit A of IX/X-bp, anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factors IX (F9) and factor X (10) in the presence of calcium with a 1 to 1 stoichiometry.<ref>PMID:2613688</ref> <ref>PMID:7925387</ref> <ref>PMID:8749314</ref> When linked to subunit A of IX-bp, anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factor IX (but not to factor X) in the presence of calcium with a 1 to 1 stoichiometry.<ref>PMID:2613688</ref> <ref>PMID:7925387</ref> <ref>PMID:8749314</ref>
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[[https://www.uniprot.org/uniprot/IXXB_PROFL IXXB_PROFL]] When linked to subunit A of IX/X-bp, anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factors IX (F9) and factor X (10) in the presence of calcium with a 1 to 1 stoichiometry.<ref>PMID:2613688</ref> <ref>PMID:7925387</ref> <ref>PMID:8749314</ref> When linked to subunit A of IX-bp, anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factor IX (but not to factor X) in the presence of calcium with a 1 to 1 stoichiometry.<ref>PMID:2613688</ref> <ref>PMID:7925387</ref> <ref>PMID:8749314</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 11:07, 4 August 2021

CRYSTAL STRUCTURE OF COAGULATION FACTORS IX/X-BINDING PROTEIN (IX/X-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS

PDB ID 1ixx

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