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1hhn
From Proteopedia
(Difference between revisions)
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<StructureSection load='1hhn' size='340' side='right'caption='[[1hhn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1hhn' size='340' side='right'caption='[[1hhn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1hhn]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1hhn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HHN FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhn OCA], [https://pdbe.org/1hhn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hhn RCSB], [https://www.ebi.ac.uk/pdbsum/1hhn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhn ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CALR_RAT CALR_RAT]] Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 10:49, 4 August 2021
Calreticulin P-domain
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