5ykj

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Current revision (07:46, 17 October 2024) (edit) (undo)
 
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<StructureSection load='5ykj' size='340' side='right'caption='[[5ykj]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
<StructureSection load='5ykj' size='340' side='right'caption='[[5ykj]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ykj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YKJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ykj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YKJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRX1, YBL064C, YBL0503, YBL0524 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ykj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ykj OCA], [https://pdbe.org/5ykj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ykj RCSB], [https://www.ebi.ac.uk/pdbsum/5ykj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ykj ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ykj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ykj OCA], [http://pdbe.org/5ykj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ykj RCSB], [http://www.ebi.ac.uk/pdbsum/5ykj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ykj ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRX1_YEAST PRX1_YEAST]] Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Involved in mitochondrial protection of cadmium-induced oxidative stress.<ref>PMID:10821871</ref> <ref>PMID:19332553</ref> <ref>PMID:20059400</ref>
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[https://www.uniprot.org/uniprot/PRX1_YEAST PRX1_YEAST] Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Involved in mitochondrial protection of cadmium-induced oxidative stress.<ref>PMID:10821871</ref> <ref>PMID:19332553</ref> <ref>PMID:20059400</ref>
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==See Also==
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*[[Peroxiredoxin 3D structures|Peroxiredoxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peroxiredoxin]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Bao, R]]
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[[Category: Bao R]]
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[[Category: He, L H]]
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[[Category: He LH]]
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[[Category: Li, C C]]
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[[Category: Li CC]]
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[[Category: Li, T]]
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[[Category: Li T]]
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[[Category: Liu, L]]
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[[Category: Liu L]]
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[[Category: Peng, C T]]
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[[Category: Peng CT]]
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[[Category: Song, Y J]]
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[[Category: Song YJ]]
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[[Category: Yang, J]]
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[[Category: Yang J]]
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[[Category: Yang, M J]]
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[[Category: Yang MJ]]
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[[Category: Zhao, C]]
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[[Category: Zhao C]]
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[[Category: Zhao, N L]]
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[[Category: Zhao NL]]
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[[Category: Zhu, Y B]]
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[[Category: Zhu YB]]
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[[Category: 1-cys peroxiredoxin]]
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[[Category: Glutathione]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Thioredoxin]]
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[[Category: Transferase]]
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Current revision

Structural basis of the thiol resolving mechanism in yeast mitochondrial 1-Cys peroxiredoxin via glutathione/thioredoxin systems

PDB ID 5ykj

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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