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6ofc
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with Sulfonamide derivative 1, pyrophosphate, and glutamine== | |
| - | + | <StructureSection load='6ofc' size='340' side='right'caption='[[6ofc]], [[Resolution|resolution]] 3.14Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ofc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OFC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SFH:5-O-[(pyridine-3-carbonyl)sulfamoyl]adenosine'>SFH</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ofb|6ofb]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_synthase_(glutamine-hydrolyzing) NAD(+) synthase (glutamine-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.1 6.3.5.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ofc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ofc OCA], [http://pdbe.org/6ofc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ofc RCSB], [http://www.ebi.ac.uk/pdbsum/6ofc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ofc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NADE_MYCTO NADE_MYCTO]] Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.[HAMAP-Rule:MF_02090] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chuenchor, W]] | ||
| + | [[Category: Doukov, T I]] | ||
| + | [[Category: Gerratana, B]] | ||
| + | [[Category: Ammonia tunneling]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Enzyme]] | ||
| + | [[Category: Gat]] | ||
| + | [[Category: Glutaminase]] | ||
| + | [[Category: Glutamine-amido transferase]] | ||
| + | [[Category: Glutamine-dependent nad+ synthetase]] | ||
| + | [[Category: Inhibitor complex]] | ||
| + | [[Category: Ligase]] | ||
| + | [[Category: Nad synthetase 1]] | ||
| + | [[Category: Nad+ synthetase]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Tuberculosis]] | ||
Revision as of 07:36, 8 January 2020
Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with Sulfonamide derivative 1, pyrophosphate, and glutamine
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Categories: Large Structures | Chuenchor, W | Doukov, T I | Gerratana, B | Ammonia tunneling | Atp-binding | Enzyme | Gat | Glutaminase | Glutamine-amido transferase | Glutamine-dependent nad+ synthetase | Inhibitor complex | Ligase | Nad synthetase 1 | Nad+ synthetase | Nucleotide-binding | Tuberculosis
