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5b8i

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<StructureSection load='5b8i' size='340' side='right'caption='[[5b8i]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='5b8i' size='340' side='right'caption='[[5b8i]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5b8i]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Cocim Cocim]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B8I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B8I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5b8i]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Coccidioides_immitis_RS Coccidioides immitis RS]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B8I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B8I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FK5:8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN'>FK5</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FK5:8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN'>FK5</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CIMG_06667 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=246410 COCIM]), CIMG_02704 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=246410 COCIM]), CIMG_08666 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=246410 COCIM])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b8i OCA], [https://pdbe.org/5b8i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b8i RCSB], [https://www.ebi.ac.uk/pdbsum/5b8i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b8i ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b8i OCA], [http://pdbe.org/5b8i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b8i RCSB], [http://www.ebi.ac.uk/pdbsum/5b8i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b8i ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/J3K8M7_COCIM J3K8M7_COCIM]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cocim]]
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[[Category: Coccidioides immitis RS]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Dranow DM]]
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[[Category: Dranow, D M]]
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[[Category: Edwards TE]]
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[[Category: Edwards, T E]]
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[[Category: Fox III D]]
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[[Category: III, D Fox]]
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[[Category: Lorimer DD]]
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[[Category: Lorimer, D D]]
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[[Category: Structural genomic]]
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[[Category: Beryllium]]
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[[Category: Calcineurin]]
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[[Category: Fk506]]
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[[Category: Fkbp12]]
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[[Category: Hydrolase]]
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[[Category: Niaid]]
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[[Category: Nih]]
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[[Category: Phosphatase]]
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[[Category: Sbri]]
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[[Category: Ssgcid]]
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[[Category: Uw]]
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Revision as of 06:41, 31 May 2023

Crystal structure of Calcineurin A and Calcineurin B in complex with FKBP12 and FK506 from Coccidioides immitis RS

PDB ID 5b8i

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