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1lfa
From Proteopedia
(Difference between revisions)
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<StructureSection load='1lfa' size='340' side='right'caption='[[1lfa]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='1lfa' size='340' side='right'caption='[[1lfa]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1lfa]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1lfa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LFA FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lfa OCA], [https://pdbe.org/1lfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lfa RCSB], [https://www.ebi.ac.uk/pdbsum/1lfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lfa ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN]] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Art:Molecular Sculpture|Art:Molecular Sculpture]] | *[[Art:Molecular Sculpture|Art:Molecular Sculpture]] | ||
| - | *[[Byron's Bender|Byron's Bender]] | ||
*[[Hydrogen in macromolecular models|Hydrogen in macromolecular models]] | *[[Hydrogen in macromolecular models|Hydrogen in macromolecular models]] | ||
*[[Integrin 3D structures|Integrin 3D structures]] | *[[Integrin 3D structures|Integrin 3D structures]] | ||
Revision as of 06:43, 18 August 2021
CD11A I-DOMAIN WITH BOUND MN++
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