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1koe

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<StructureSection load='1koe' size='340' side='right'caption='[[1koe]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='1koe' size='340' side='right'caption='[[1koe]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1koe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KOE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1koe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KOE FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1koe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1koe OCA], [http://pdbe.org/1koe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1koe RCSB], [http://www.ebi.ac.uk/pdbsum/1koe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1koe ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1koe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1koe OCA], [https://pdbe.org/1koe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1koe RCSB], [https://www.ebi.ac.uk/pdbsum/1koe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1koe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/COIA1_MOUSE COIA1_MOUSE]] Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
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[[https://www.uniprot.org/uniprot/COIA1_MOUSE COIA1_MOUSE]] Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 10:34, 31 March 2021

ENDOSTATIN

PDB ID 1koe

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