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1lhn

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<StructureSection load='1lhn' size='340' side='right'caption='[[1lhn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1lhn' size='340' side='right'caption='[[1lhn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1lhn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LHN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LHN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1lhn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LHN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AON:5-ALPHA-ANDROSTANE-3-BETA,17-ALPHA-DIOL'>AON</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AON:5-ALPHA-ANDROSTANE-3-BETA,17-ALPHA-DIOL'>AON</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1d2s|1d2s]], [[1f5f|1f5f]], [[1kdk|1kdk]], [[1kdm|1kdm]], [[1lho|1lho]], [[1lhu|1lhu]], [[1lhv|1lhv]], [[1lhw|1lhw]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1d2s|1d2s]], [[1f5f|1f5f]], [[1kdk|1kdk]], [[1kdm|1kdm]], [[1lho|1lho]], [[1lhu|1lhu]], [[1lhv|1lhv]], [[1lhw|1lhw]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lhn OCA], [http://pdbe.org/1lhn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lhn RCSB], [http://www.ebi.ac.uk/pdbsum/1lhn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1lhn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lhn OCA], [https://pdbe.org/1lhn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lhn RCSB], [https://www.ebi.ac.uk/pdbsum/1lhn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lhn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SHBG_HUMAN SHBG_HUMAN]] Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
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[[https://www.uniprot.org/uniprot/SHBG_HUMAN SHBG_HUMAN]] Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 06:44, 18 August 2021

CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 5ALPHA-ANDROSTANE-3BETA,17ALPHA-DIOL

PDB ID 1lhn

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