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Penicillin-binding protein 3D structures
From Proteopedia
(Difference between revisions)
(New page: ==3D structures of penicillin-binding protein== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *'''Penicillin-bind...) |
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *'''Penicillin-binding protein''' | + | *'''Penicillin-binding protein'''; Domains - transpeptidase (TP) 234-588 |
**[[1qme]], [[1rp5]], [[2z2l]], [[5oau]] – SpPBP 2X – ''Streptococcus pneumoniae''<br /> | **[[1qme]], [[1rp5]], [[2z2l]], [[5oau]] – SpPBP 2X – ''Streptococcus pneumoniae''<br /> | ||
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**[[2wad]], [[2wae]], [[2waf]] – SpPBP 2B<br /> | **[[2wad]], [[2wae]], [[2waf]] – SpPBP 2B<br /> | ||
**[[3vma]] – EcPBP 1B - ''Escherichia coli''<br /> | **[[3vma]] – EcPBP 1B - ''Escherichia coli''<br /> | ||
| - | **[[6g5r]], [[6fzk]] – EcPBP 1B UB2H domain – NMR<br /> | + | **[[6g5r]], [[6fzk]] – EcPBP 1B UB2H domain 108-200 – NMR<br /> |
**[[4bjp]] – EcPBP 3 residues 67-577<br /> | **[[4bjp]] – EcPBP 3 residues 67-577<br /> | ||
| + | **[[6hzq]] – EcPBP 3 TP domain <br /> | ||
**[[4bjq]] – EcPBP 3 residues 88-165<br /> | **[[4bjq]] – EcPBP 3 residues 88-165<br /> | ||
**[[2ex2]] – EcPBP 4<br /> | **[[2ex2]] – EcPBP 4<br /> | ||
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**[[1hd8]], [[1nj4]], [[1sdn]] – EcPBP 5 (mutant) <br /> | **[[1hd8]], [[1nj4]], [[1sdn]] – EcPBP 5 (mutant) <br /> | ||
**[[3it9]] – EcPBP 6<br /> | **[[3it9]] – EcPBP 6<br /> | ||
| - | **[[5tro]] - SaPBP 1 dimerization and | + | **[[5tro]] - SaPBP 1 dimerization and TP domains – ''Staphylococcus aureus''<br /> |
**[[1mwr]], [[1vqq]], [[4bl2]], [[4bl3]], [[4cpk]] - SaPBP 2A (mutant) <br /> | **[[1mwr]], [[1vqq]], [[4bl2]], [[4bl3]], [[4cpk]] - SaPBP 2A (mutant) <br /> | ||
**[[2olu]], [[3dwk]], [[5m1a]], [[5m19]], [[5m18]] – SaPBP 2<br /> | **[[2olu]], [[3dwk]], [[5m1a]], [[5m19]], [[5m18]] – SaPBP 2<br /> | ||
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**[[3equ]] – NgPBP 2 – ''Neisseria gonorrhoeae''<br /> | **[[3equ]] – NgPBP 2 – ''Neisseria gonorrhoeae''<br /> | ||
**[[3eqv]], [[5ksh]] – NgPBP 2 (mutant) <br /> | **[[3eqv]], [[5ksh]] – NgPBP 2 (mutant) <br /> | ||
| - | **[[6p52]], [[6p53]] – NgPBP 2 | + | **[[6p52]], [[6p53]] – NgPBP 2 TP domain<br /> |
| - | **[[6p56]], [[4u3t]] – NgPBP 2 | + | **[[6p56]], [[4u3t]] – NgPBP 2 TP domain (mutant)<br /> |
**[[5u2g]] – HiPBP 1A – ''Haemophilus influenza''<br /> | **[[5u2g]] – HiPBP 1A – ''Haemophilus influenza''<br /> | ||
| + | **[[6hzo]] – HiPBP 3 TP domain<br /> | ||
**[[3a3d]] – HiPBP 4 <br /> | **[[3a3d]] – HiPBP 4 <br /> | ||
**[[3a3j]] – HiPBP 5<br /> | **[[3a3j]] – HiPBP 5<br /> | ||
**[[3lo7]], [[3un7]], [[5crf]] – MtPBP A – ''Mycobacterium tuberculosis''<br /> | **[[3lo7]], [[3un7]], [[5crf]] – MtPBP A – ''Mycobacterium tuberculosis''<br /> | ||
| - | **[[3oc2]], [[3pbn]], [[6hr4]] – PaPBP 3 – ''Pseudomonas aeruginosa''<br /> | + | **[[6kgh]] – MtPBP 3<br /> |
| + | **[[3oc2]], [[3pbn]], [[6hr4]], [[6hzr]] – PaPBP 3 – ''Pseudomonas aeruginosa''<br /> | ||
| + | **[[6r40]] - PaPBP 3 (mutant)<br /> | ||
**[[3tg9]] – PBP – ''Bacillus halodurans''<br /> | **[[3tg9]] – PBP – ''Bacillus halodurans''<br /> | ||
**[[3udf]] – AbPBP – ''Acinetobacter baumannii''<br /> | **[[3udf]] – AbPBP – ''Acinetobacter baumannii''<br /> | ||
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**[[6bsq]] - EfPBP 4<br /> | **[[6bsq]] - EfPBP 4<br /> | ||
**[[6g0k]] - EfPBP 5 (mutant)<br /> | **[[6g0k]] - EfPBP 5 (mutant)<br /> | ||
| - | **[[5lp4]] – HpPBP 2 – ''Helicobacter | + | **[[5lp4]] – HpPBP 2 – ''Helicobacter pylori''<br /> |
| + | **[[6hzh]] – CtPBP 3 TP domain – ''Chlamydia trachomatis''<br /> | ||
| + | **[[6hzi]] – PBP 3 TP domain – ''Burkholderia pseudomallei''<br /> | ||
*Penicillin-binding protein complex with antibiotics | *Penicillin-binding protein complex with antibiotics | ||
**[[1qmf]], [[2z2m]], [[2zc3]], [[2zc4]], [[2zc5]], [[2zc6]], [[5oj1]], [[5oj0]], [[5oiz]] – SpPBP 2X + antibiotic<br /> | **[[1qmf]], [[2z2m]], [[2zc3]], [[2zc4]], [[2zc5]], [[2zc6]], [[5oj1]], [[5oj0]], [[5oiz]] – SpPBP 2X + antibiotic<br /> | ||
| + | **[[2c5w]] - SpPBP 1A + antibiotic<br /> | ||
| + | **[[2jch]], [[2je5]], [[2xd1]] - SpPBP 1B (mutant) + antibiotic<br /> | ||
**[[1mwu]], [[1mwt]], [[1mws]] - SaPBP 2A (mutant) + antibiotic<br /> | **[[1mwu]], [[1mwt]], [[1mws]] - SaPBP 2A (mutant) + antibiotic<br /> | ||
**[[2uwx]] - SaPBP 1B (mutant) + antibiotic<br /> | **[[2uwx]] - SaPBP 1B (mutant) + antibiotic<br /> | ||
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**[[5txi]], [[5ty7]], [[5tw8]] - SaPBP 4 + antibiotic<br /> | **[[5txi]], [[5ty7]], [[5tw8]] - SaPBP 4 + antibiotic<br /> | ||
**[[3hum]], [[3hun]], [[5ty2]], [[5tx9]], [[5tw4]] - SaPBP 4 (mutant) + antibiotic<br /> | **[[3hum]], [[3hun]], [[5ty2]], [[5tx9]], [[5tw4]] - SaPBP 4 (mutant) + antibiotic<br /> | ||
| - | **[[ | + | **[[6i1i]] – EcPBP 3 TP domain + antibiotic<br /> |
| - | + | ||
**[[2ex6]], [[2ex8]], [[2ex9]], [[2exa]], [[2exb]] - EcPBP 4 + antibiotic<br /> | **[[2ex6]], [[2ex8]], [[2ex9]], [[2exa]], [[2exb]] - EcPBP 4 + antibiotic<br /> | ||
**[[3beb]], [[3bec]], [[3mzd]], [[3mze]], [[3mzf]] - EcPBP 5 + antibiotic<br /> | **[[3beb]], [[3bec]], [[3mzd]], [[3mze]], [[3mzf]] - EcPBP 5 + antibiotic<br /> | ||
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**[[3a3e]], [[3a3f]], [[3a3i]] – HiPBP 4 + antibiotic<br /> | **[[3a3e]], [[3a3f]], [[3a3i]] – HiPBP 4 + antibiotic<br /> | ||
**[[4oon]] – PaPBP 1A + antibiotic<br /> | **[[4oon]] – PaPBP 1A + antibiotic<br /> | ||
| - | **[[3ocl]], [[3ocn]], [[3pbo]], [[3pbq]], [[3pbr]], [[3pbs]], [[3pbt]], [[4kqo]], [[4kqq]], [[4kqr]], [[4l0l]], [[6un1]], [[6hr6]] – PaPBP 3 + antibiotic<br /> | + | **[[3ocl]], [[3ocn]], [[3pbo]], [[3pbq]], [[3pbr]], [[3pbs]], [[3pbt]], [[4kqo]], [[4kqq]], [[4kqr]], [[4l0l]], [[6un1]], [[6hr6]], [[6i1e]], [[6r3x]], [[6un3]], [[6vje]] – PaPBP 3 + antibiotic<br /> |
| - | **[[6hr9]] – PaPBP 3 (mutant) + antibiotic<br /> | + | **[[6hr9]], [[6r42]] – PaPBP 3 (mutant) + antibiotic<br /> |
**[[3nb6]], [[3nb7]] - AaPBP 1A + antibiotic<br /> | **[[3nb6]], [[3nb7]] - AaPBP 1A + antibiotic<br /> | ||
**[[3udi]], [[3udx]], [[3ue0]], [[3ue1]] - AbPBP + antibiotic<br /> | **[[3udi]], [[3udx]], [[3ue0]], [[3ue1]] - AbPBP + antibiotic<br /> | ||
**[[3upn]], [[3upp]], [[5cxw]] - MtPBP A + antibiotic<br /> | **[[3upn]], [[3upp]], [[5cxw]] - MtPBP A + antibiotic<br /> | ||
**[[3upo]] - MtPBP A (mutant) + antibiotic<br /> | **[[3upo]] - MtPBP A (mutant) + antibiotic<br /> | ||
| + | **[[6kgs]], [[6kgt]], [[6kgu]], [[6kgv]], [[6kgw]] – MtPBP 3 + antibiotic<br /> | ||
**[[3zg8]], [[3zg9]], [[3zga]] - LmPBP 4 + antibiotic<br /> | **[[3zg8]], [[3zg9]], [[3zga]] - LmPBP 4 + antibiotic<br /> | ||
**[[6mkh]], [[6mki]], [[6bsr]] - EfPBP 4 + antibiotic<br /> | **[[6mkh]], [[6mki]], [[6bsr]] - EfPBP 4 + antibiotic<br /> | ||
**[[6g88]] - EfPBP 5 + antibiotic<br /> | **[[6g88]] - EfPBP 5 + antibiotic<br /> | ||
| - | **[[6p54]], [[6p55]] – NgPBP 2 | + | **[[6p54]], [[6p55]] – NgPBP 2 TP domain + antibiotic<br /> |
| + | **[[6i1f]], [[6i1g]], [[6i1h]] – CtPBP 3 TP domain + antibiotic<br /> | ||
*Penicillin-binding protein complex with boronic acid derivatives | *Penicillin-binding protein complex with boronic acid derivatives | ||
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**[[3zg5]] - SaPBP + peptidoglycan analog<br /> | **[[3zg5]] - SaPBP + peptidoglycan analog<br /> | ||
| - | *Penicillin-binding protein | + | *Penicillin-binding protein other complexes |
| - | **[[4fsf]], [[4wel]], [[4wej]] - PaPBP 3 + inhibitor<br /> | + | **[[4fsf]], [[4wel]], [[4wej]], [[6vot]], [[6y6u]], [[6y6z]] - PaPBP 3 + inhibitor<br /> |
**[[4wek]] – PaPBP 3 (mutant) + inhibitor<br /> | **[[4wek]] – PaPBP 3 (mutant) + inhibitor<br /> | ||
**[[5fgz]] – EcPBP 1B + inhibitor<br /> | **[[5fgz]] – EcPBP 1B + inhibitor<br /> | ||
| + | **[[6g9f]], [[6g9p]], [[6g9s]] – EcPBP 2 + inhibitor<br /> | ||
**[[4cjn]] – SaPBP 2A + quinazolinine derivative<br /> | **[[4cjn]] – SaPBP 2A + quinazolinine derivative<br /> | ||
**[[6g9f]], [[6g9p]], [[6g9s]] – EcPBP 2 + inhibitor<br /> | **[[6g9f]], [[6g9p]], [[6g9s]] – EcPBP 2 + inhibitor<br /> | ||
**[[5lp5]] – HpPBP 2 + MREC <br /> | **[[5lp5]] – HpPBP 2 + MREC <br /> | ||
| + | **[[6pl5]], [[6pl6]] - PBP 2 + PGT + peptide – ''Thermus thermophilus''<br /> | ||
*PBP D-alanyl-D-alanine carboxypeptidase or DD-transpeptidase | *PBP D-alanyl-D-alanine carboxypeptidase or DD-transpeptidase | ||
Revision as of 09:17, 17 September 2020
3D structures of penicillin-binding protein
Updated on 17-September-2020
