We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

Sandbox GGC12

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 7: Line 7:
== Function ==
== Function ==
-
The TBP, TATA-binding protein, is a factor in the process of Transcription within Eukaryotes. This binding protein is a subunit in the family of TFIID. The function of the TBP is to bind to a DNA sequence which is the TATA box. This allows RNA Polymerase II to bind to the promoter. This is the beginning of the process of Transcription.
+
The TATA-Binding protein, TBP, is a factor in the process of Transcription within Eukaryotes. This binding protein is a subunit in the family of TFIID. The function of the TBP is to bind to a DNA sequence which is the TATA box. This allows RNA Polymerase II to bind to the promoter. This is the beginning of the process of Transcription.
-
== Disease ==
+
== Relevance ==
 +
 
 +
The TATA-Binding Protein is relevant to everyday life because humans contain this specific protein as well with or without a promoter. This process is happening in multiple tissues and cells at a time.
== Interesting Facts about the TBP ==
== Interesting Facts about the TBP ==
-The first ever for the TBP was found in fruit flies, specifically Drosophila flies.
-The first ever for the TBP was found in fruit flies, specifically Drosophila flies.
 +
-This is not the same idea in prokaryotes. Prokaryotes have a different concept because it is a Pribnow box instead of a TATA box.
-This is not the same idea in prokaryotes. Prokaryotes have a different concept because it is a Pribnow box instead of a TATA box.
 +
-Another name for the TATA box is the Goldberg- Hogness box.
-Another name for the TATA box is the Goldberg- Hogness box.
 +
== Structural highlights ==
== Structural highlights ==

Revision as of 12:28, 20 November 2019

TATA-Binding Protein (TBP)

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
Personal tools