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== Structure ==
== Structure ==
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The structure of the TBP has an internal pseudo-symmetry which contains two 88- amino acid repeats. This structure attaches to a DNA structure of deformity in the helix. The DNA structure's minor groove is opened wide to have complete access for the TBP to bind within it.
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The structure of the TBP has a pseudo-symmetry within its structure which contains two 88- amino acid repeats. This structure attaches to a DNA structure of deformity in the helix; the deformity is for the purpose of binding. The DNA structure's minor groove is open- wide to have complete access for the TBP to bind within it.
== Function ==
== Function ==

Revision as of 13:03, 20 November 2019

TATA-Binding Protein (TBP)

Caption for this structure

Drag the structure with the mouse to rotate

References

Kim, J., & Iyer, V. R. (2004). Global role of TATA box-binding protein recruitment to promoters in mediating gene expression profiles. Molecular and cellular biology, 24(18), 8104–8112. doi:10.1128/MCB.24.18.8104-8112.2004

Juo, Zong Sean, et al. “How Proteins Recognize the TATA Box.” Journal of Molecular Biology, vol. 261, no. 2, 1996, pp. 239–254., doi:10.1006/jmbi.1996.0456.

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