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1n8o
From Proteopedia
(Difference between revisions)
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<StructureSection load='1n8o' size='340' side='right'caption='[[1n8o]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1n8o' size='340' side='right'caption='[[1n8o]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1n8o]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1n8o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N8O FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1azz|1azz]], [[1ecy|1ecy]], [[1fi8|1fi8]], [[1id5|1id5]], [[1ifg|1ifg]], [[1slu|1slu]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1azz|1azz]], [[1ecy|1ecy]], [[1fi8|1fi8]], [[1id5|1id5]], [[1ifg|1ifg]], [[1slu|1slu]]</div></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n8o OCA], [https://pdbe.org/1n8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n8o RCSB], [https://www.ebi.ac.uk/pdbsum/1n8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n8o ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ECOT_ECOLI ECOT_ECOLI]] General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. The strength of inhibition does not appear to be correlated with a particular protease specificity.[HAMAP-Rule:MF_00706] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 06:59, 25 August 2021
Crystal structure of a complex between bovine chymotrypsin and ecotin
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