1neb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='1neb' size='340' side='right'caption='[[1neb]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
<StructureSection load='1neb' size='340' side='right'caption='[[1neb]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1neb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NEB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NEB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1neb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NEB FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1neb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1neb OCA], [http://pdbe.org/1neb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1neb RCSB], [http://www.ebi.ac.uk/pdbsum/1neb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1neb ProSAT]</span></td></tr>
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1neb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1neb OCA], [https://pdbe.org/1neb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1neb RCSB], [https://www.ebi.ac.uk/pdbsum/1neb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1neb ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/NEBU_HUMAN NEBU_HUMAN]] Defects in NEB are the cause of nemaline myopathy type 2 (NEM2) [MIM:[http://omim.org/entry/256030 256030]]. A form of nemaline myopathy. Nemaline myopathies are muscular disorders characterized by muscle weakness of varying severity and onset, and abnormal thread-or rod-like structures in muscle fibers on histologic examination.<ref>PMID:10051637</ref>
+
[[https://www.uniprot.org/uniprot/NEBU_HUMAN NEBU_HUMAN]] Defects in NEB are the cause of nemaline myopathy type 2 (NEM2) [MIM:[https://omim.org/entry/256030 256030]]. A form of nemaline myopathy. Nemaline myopathies are muscular disorders characterized by muscle weakness of varying severity and onset, and abnormal thread-or rod-like structures in muscle fibers on histologic examination.<ref>PMID:10051637</ref>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NEBU_HUMAN NEBU_HUMAN]] This giant muscle protein may be involved in maintaining the structural integrity of sarcomeres and the membrane system associated with the myofibrils. Binds and stabilize F-actin.
+
[[https://www.uniprot.org/uniprot/NEBU_HUMAN NEBU_HUMAN]] This giant muscle protein may be involved in maintaining the structural integrity of sarcomeres and the membrane system associated with the myofibrils. Binds and stabilize F-actin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 07:01, 25 August 2021

SH3 DOMAIN FROM HUMAN NEBULIN, NMR, MINIMIZED AVERAGE STRUCTURE

PDB ID 1neb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools