Phosphoserine aminotransferase

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Line 18: Line 18:
**[[3m5u]] – PSAT – ''Campylobacter jejuni''<br />
**[[3m5u]] – PSAT – ''Campylobacter jejuni''<br />
**[[3qm2]] – PSAT – ''Salmonella enterica''<br />
**[[3qm2]] – PSAT – ''Salmonella enterica''<br />
-
**[[5yii]] - EhPSAT – Entamoeba histolytica<br />
+
**[[5yii]] - EhPSAT – ''Entamoeba histolytica''<br />
*Phosphoserine aminotransferase complex with pyridoxal phosphate
*Phosphoserine aminotransferase complex with pyridoxal phosphate
Line 33: Line 33:
**[[5yb0]] - EhPSAT + PLP <br />
**[[5yb0]] - EhPSAT + PLP <br />
**[[5yd2]] - EhPSAT (mutant) + PLP<br />
**[[5yd2]] - EhPSAT (mutant) + PLP<br />
 +
**[[6xdk]] - PSAT + PLP – ''Stenotrophomonas maltophilia''<br />
*Phosphoserine aminotransferase ternary complex
*Phosphoserine aminotransferase ternary complex

Revision as of 08:03, 23 September 2020

Phosphoserine aminotransferase dimer complex with pyridoxal phosphate, triethylene glycol, Hepes, Cl- and Mg+2 ions (PDB entry 1w23)

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3D structures of phosphoserine aminotransferase

Updated on 23-September-2020

References

  1. Basurko MJ, Marche M, Darriet M, Cassaigne A. Phosphoserine aminotransferase, the second step-catalyzing enzyme for serine biosynthesis. IUBMB Life. 1999 Nov;48(5):525-9. PMID:10637769 doi:http://dx.doi.org/10.1080/713803557
  2. Vie N, Copois V, Bascoul-Mollevi C, Denis V, Bec N, Robert B, Fraslon C, Conseiller E, Molina F, Larroque C, Martineau P, Del Rio M, Gongora C. Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells. Mol Cancer. 2008 Jan 25;7:14. doi: 10.1186/1476-4598-7-14. PMID:18221502 doi:http://dx.doi.org/10.1186/1476-4598-7-14
  3. Dubnovitsky AP, Kapetaniou EG, Papageorgiou AC. Enzyme adaptation to alkaline pH: atomic resolution (1.08 A) structure of phosphoserine aminotransferase from Bacillus alcalophilus. Protein Sci. 2005 Jan;14(1):97-110. PMID:15608117 doi:14/1/97

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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