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Pre-mRNA-splicing factor
From Proteopedia
(Difference between revisions)
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</StructureSection> | </StructureSection> | ||
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| - | == 3D Structures of pre-mRNA splicing factors == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Pre-mRNA-splicing factor 2 | ||
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| - | **[[3beg]] – hPrp P33 subunit + Ser/Thr-protein kinase – human<BR /> | ||
| - | **[[2o3d]] – hPrp P33 subunit | ||
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| - | *Pre-mRNA-splicing factor 3 | ||
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| - | **[[1x4q]] – hPrp PWI domain - NMR<BR /> | ||
| - | **[[4yhu]], [[4yhv]] – yPrp C-terminal - yeast<br /> | ||
| - | **[[4yhw]] – yPrp C-terminal + snRNA<br /> | ||
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| - | *Pre-mRNA-splicing factor 3B | ||
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| - | **[[3lqv]], [[2f9d]], [[2f9j]] – hPrp residues 377-415 + pre-mRNA branch site protein 14<BR /> | ||
| - | **[[2fho]] - hPrp residues 379-424 + spliceosomal protein P14 - NMR<BR /> | ||
| - | **[[2do5]] – hPrp subunit 2 – NMR<BR /> | ||
| - | **[[1x5t]] - hPrp subunit 4 – NMR<BR /> | ||
| - | **[[5gvq]] - hPrp subunit 4 RNA-binding domain – NMR<BR /> | ||
| - | **[[6en4]] - hPrp subunits 1,3,5 + SF3B14B<br /> | ||
| - | **[[5ife]] - hPrp subunits 1,3,5 + PHD finger-like protein 5A <br /> | ||
| - | **[[5zya]] - hPrp subunits 1,3,5 + PHD finger-like protein 5A + splicing modulator<br /> | ||
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| - | *Pre-mRNA-splicing factor 8 | ||
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| - | **[[3lru]] – hPrp residues 1831-1990<br /> | ||
| - | **[[3e9l]], [[3enb]] – hPrp endonuclease domain<br /> | ||
| - | **[[3sbt]], [[4ilh]] – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 <br /> | ||
| - | **[[4jk7]], [[4jk9]], [[3e9o]], [[3e9p]], [[3e66]] - yPrp RNA-binding domain <br /> | ||
| - | **[[4ilj]], [[4jk8]], [[4jka]], [[4jkb]], [[4jkc]], [[4jkd]], [[4jke]], [[4jkf]], [[4jkg]], [[4jkh]] - yPrp RNA-binding domain (mutant)<br /> | ||
| - | **[[3zef]], [[4i43]] – yPrp + A1 cistron-splicing factor AAR2<br /> | ||
| - | **[[2og4]], [[3sbg]] - yPrp Jab1/MPN domain<br /> | ||
| - | **[[4bgd]], [[5dca]], [[5m52]], [[5m5p]] – yPrp Jab1/MPN domain + pre-mRNA-splicing helicase BRR2<br /> | ||
| - | **[[4kit]] – yPrp Jab1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br /> | ||
| - | **[[4ilg]] – yPrp Jab1/MPN+RNA-binding domains + A1 cistron-splicing factor AAR2 <br /> | ||
| - | **[[6nqi]] – Prp RH domain – red alga <br /> | ||
| - | **[[2p8r]] – CePrp C terminal (mutant) – ''Caenorhabditis elegans''<br /> | ||
| - | **[[2p87]] – CePrp C terminal <br /> | ||
| - | **[[6mwy]] – Prp – ''Cryptococcus gattii'' <br /> | ||
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| - | *Pre-mRNA-splicing factor 9 | ||
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| - | **[[4dgw]] – yPrp + Prp 21 + Prp 11 | ||
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| - | *Pre-mRNA-splicing factor 11 | ||
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| - | **[[4dgw]] – yPrp + Prp 21 + Prp 9 | ||
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| - | *Pre-mRNA-splicing factor 18 | ||
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| - | **[[2dk4]] – hPrp splicing factor motif domain - NMR<BR /> | ||
| - | **[[1dvk]] – yPrp functional domain <br /> | ||
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| - | *Pre-mRNA-splicing factor 19 | ||
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| - | **[[3lrv]] – yPrp WD40 domain<BR /> | ||
| - | **[[2bay]] – yPrp U-box<BR /> | ||
| - | **[[1n87]] - yPrp U-box - NMR<BR /> | ||
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| - | *Pre-mRNA-splicing factor 20 | ||
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| - | **[[2i38]] - hPrp RNA-binding domain (mutant) – NMR<BR /> | ||
| - | **[[2i2y]] – Prp RNA-binding domain + RNA – ''Streptococcus'' – NMR<BR /> | ||
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| - | *Pre-mRNA-splicing factor 21 | ||
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| - | **[[4dgw]] – yPrp + Prp 9 + Prp 11 | ||
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| - | *snRNA-associated-splicing factor 24 | ||
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| - | **[[2l9w]] – yPrp C terminal – NMR<BR /> | ||
| - | **[[2kh9]] – yPrp residues 115-197 + RNA – NMR<BR /> | ||
| - | **[[2go9]] – yPrp RNA-binding domains – NMR<BR /> | ||
| - | **[[2ghp]] - yPrp RNA-binding domains | ||
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| - | *Pre-mRNA-splicing factor 31 | ||
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| - | **[[2ozb]] – hPrp + RNA + tri-snRNP <br /> | ||
| - | **[[3siu]], [[3siv]] – hPrp + NHP2-like protein + snRNP <br /> | ||
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| - | *Pre-mRNA-splicing factor 38A | ||
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| - | **[[4rz9]], [[4rza]] – hPrp <br /> | ||
| - | **[[5f5s]] – hPrp + microfibrillar-associated protein 1<br /> | ||
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| - | *Pre-mRNA-splicing factor 40 | ||
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| - | **[[1o6w]] – yPrp WW domain – yeast - NMR<br /> | ||
| - | **[[2b7e]] – yPrp FF1 domain - NMR<br /> | ||
| - | **[[2kfd]] – yPrp FF4 domain - NMR<br /> | ||
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| - | *Pre-mRNA-splicing factor 43P | ||
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| - | **[[2xau]], [[3kx2]] – yPrp + ADP | ||
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| - | *Pre-mRNA-splicing factors in spliceosome | ||
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| - | **[[3jcr]], [[5o9z]], [[6id1]], [[6id0]], [[6icz]], [[6ff7]], [[6ff4]], [[6ah0]], [[5z58]] – hPrp - CryoEM<br /> | ||
| - | **[[3jb9]] – yPrp <br /> | ||
| - | **[[3jcm]], [[5gam]], [[5gan]], [[5gao]], [[5gap]], [[5gmk]], [[5lj3]], [[5lj5]], [[5lqw]], [[5mps]], [[5mq0]], [[5mqf]], [[5wsg]], [[6g90]], [[6exn]], [[6bk8]], [[5ylz]], [[5y88]], [[6j6q]], [[6j6n]], [[6j6h]], [[6j6g]], [[5zwo]] – yPrp - CryoEM<br /> | ||
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| - | *Pre-mRNA-splicing factor cwc2 | ||
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| - | **[[3tp2]], [[3u1l]], [[3u1m]] – yPrp <br /> | ||
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| - | *Pre-mRNA-splicing factor cwc26 | ||
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| - | **[[2mkc]] – yPrp + U2 SNRNP component IST3 + Pre-mRNA leakage protein<br /> | ||
| - | **[[4uqt]] – yPrp + U2 SNRNP component IST3 <br /> | ||
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| - | *Pre-mRNA-splicing factor bud31 | ||
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| - | **[[2my1]] – yPrp - NMR<br /> | ||
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| - | *Pre-mRNA-splicing factor sad1 | ||
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| - | **[[4msx]] – yPrp <br /> | ||
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| - | *Pre-mRNA-splicing factor RBM22 | ||
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| - | **[[2ytc]] – yPrp RNA-binding domain - NMR<BR /> | ||
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| - | *Pre-mRNA-splicing factor RDS3 | ||
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| - | **[[2k0a]] – yPrp - NMR<BR /> | ||
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| - | *Pre-mRNA-splicing factor URN1 | ||
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| - | **[[2juc]] – yPrp FF domain - NMR<BR /> | ||
| - | }} | ||
== References == | == References == | ||
Current revision
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References
- ↑ Misteli T, Spector DL. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol Cell. 1999 Jun;3(6):697-705. PMID:10394358
- ↑ McKie AB, McHale JC, Keen TJ, Tarttelin EE, Goliath R, van Lith-Verhoeven JJ, Greenberg J, Ramesar RS, Hoyng CB, Cremers FP, Mackey DA, Bhattacharya SS, Bird AC, Markham AF, Inglehearn CF. Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). Hum Mol Genet. 2001 Jul 15;10(15):1555-62. PMID:11468273
