Pregnane X receptor
From Proteopedia
(Difference between revisions)
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**[[1ilh]], [[2qnv]] – hPXR LBD + ligand<br /> | **[[1ilh]], [[2qnv]] – hPXR LBD + ligand<br /> | ||
| - | **[[1m13]] – hPXR LBD + | + | **[[1m13]] – hPXR LBD + anti-angiogenic<br /> |
**[[1skx]] – hPXR LBD + antibiotic<br /> | **[[1skx]] – hPXR LBD + antibiotic<br /> | ||
**[[3r8d]] – hPXR LBD + anti-HIV drug<br /> | **[[3r8d]] – hPXR LBD + anti-HIV drug<br /> | ||
| - | **[[ | + | **[[6hj2]] – hPXR LBD + cancer drug<br /> |
**[[4j5x]] – hPXR LBD + hRXR LBD + ligand<br /> | **[[4j5x]] – hPXR LBD + hRXR LBD + ligand<br /> | ||
| - | **[[3hvl]] – hPXR/steroid receptor coactivator + ligand | + | **[[3hvl]], [[6xp9]], [[6nx1]], [[1nrl]], [[2o9i]], [[5a86]], [[5x0r]], [[6hty]] – hPXR/steroid receptor coactivator peptide + ligand<br /> |
| - | + | ||
**[[4s0s]], [[4xhd]] – hPXR LBD + adnectin derivative<br /> | **[[4s0s]], [[4xhd]] – hPXR LBD + adnectin derivative<br /> | ||
**[[4s0t]] – hPXR LBD + adnectin-1 + inhibitor<br /> | **[[4s0t]] – hPXR LBD + adnectin-1 + inhibitor<br /> | ||
**[[4x1f]], [[4x1g]] – hPXR LBD + estrogen derivative<br /> | **[[4x1f]], [[4x1g]] – hPXR LBD + estrogen derivative<br /> | ||
**[[4xao]] – hPXR LBD + pesticide<br /> | **[[4xao]] – hPXR LBD + pesticide<br /> | ||
| - | **[[6s41]], [[6dup]] – hPXR LBD + inhibitor<br /> | + | **[[6s41]], [[6dup]], [[6p2b]], [[4ny9]] – hPXR LBD + inhibitor<br /> |
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:00, 7 October 2020
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3D structures of pregnane X receptor
Updated on 07-October-2020
References
- ↑ Kliewer SA, Goodwin B, Willson TM. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr Rev. 2002 Oct;23(5):687-702. PMID:12372848 doi:http://dx.doi.org/10.1210/er.2001-0038
- ↑ Koutsounas I, Theocharis S, Patsouris E, Giaginis C. Pregnane X receptor (PXR) at the crossroads of human metabolism and disease. Curr Drug Metab. 2013 Mar;14(3):341-50. PMID:23237007
- ↑ Chrencik JE, Orans J, Moore LB, Xue Y, Peng L, Collins JL, Wisely GB, Lambert MH, Kliewer SA, Redinbo MR. Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin. Mol Endocrinol. 2005 May;19(5):1125-34. Epub 2005 Feb 10. PMID:15705662 doi:10.1210/me.2004-0346
