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1pl8
From Proteopedia
(Difference between revisions)
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<StructureSection load='1pl8' size='340' side='right'caption='[[1pl8]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='1pl8' size='340' side='right'caption='[[1pl8]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1pl8]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1pl8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PL8 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pl6|1pl6]], [[1pl7|1pl7]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1pl6|1pl6]], [[1pl7|1pl7]]</div></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-iditol_2-dehydrogenase L-iditol 2-dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.14 1.1.1.14] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pl8 OCA], [https://pdbe.org/1pl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pl8 RCSB], [https://www.ebi.ac.uk/pdbsum/1pl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pl8 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DHSO_HUMAN DHSO_HUMAN]] Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm (By similarity).<ref>PMID:16278369</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 09:31, 8 September 2021
human SDH/NAD+ complex
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Categories: Human | L-iditol 2-dehydrogenase | Large Structures | Adams, P D | Beebe, D A | Chrunyk, B | Cunningham, D | Ekstrom, J L | Griffor, M | Kamath, A | Lee, S E | Madura, R | Mcguire, D | Mylari, B L | Oates, P J | Pauly, T A | Rath, V L | Subashi, T | Wasilko, D | Watts, P | Human sorbitol dehydrogenase | Nad | Oxidoreductase
