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1qfp
From Proteopedia
(Difference between revisions)
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<StructureSection load='1qfp' size='340' side='right'caption='[[1qfp]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='1qfp' size='340' side='right'caption='[[1qfp]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1qfp]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1qfp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QFP FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qfp OCA], [https://pdbe.org/1qfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qfp RCSB], [https://www.ebi.ac.uk/pdbsum/1qfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qfp ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SN_MOUSE SN_MOUSE]] Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells (By similarity). Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.<ref>PMID:15364954</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 09:55, 15 September 2021
N-TERMINAL DOMAIN OF SIALOADHESIN (MOUSE)
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