6pyf
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Sex Hormone-binding globulin mutant E176K in complex with Estradiol== | |
| - | + | <StructureSection load='6pyf' size='340' side='right'caption='[[6pyf]], [[Resolution|resolution]] 1.73Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6pyf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PYF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PYF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EST:ESTRADIOL'>EST</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pyf OCA], [http://pdbe.org/6pyf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pyf RCSB], [http://www.ebi.ac.uk/pdbsum/6pyf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pyf ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SHBG_HUMAN SHBG_HUMAN]] Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Das, S]] | ||
| + | [[Category: Petegem, F Van]] | ||
| + | [[Category: Round, P W]] | ||
| + | [[Category: Wu, T S]] | ||
| + | [[Category: Binding globulin]] | ||
| + | [[Category: Hormone]] | ||
| + | [[Category: Sex steroid]] | ||
| + | [[Category: Transport]] | ||
Revision as of 09:13, 25 December 2019
Sex Hormone-binding globulin mutant E176K in complex with Estradiol
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