6teo

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'''Unreleased structure'''
 
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The entry 6teo is ON HOLD until Paper Publication
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==Crystal structure of a yeast Snu114-Prp8 complex==
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<StructureSection load='6teo' size='340' side='right'caption='[[6teo]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6teo]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TEO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TEO FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6teo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6teo OCA], [http://pdbe.org/6teo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6teo RCSB], [http://www.ebi.ac.uk/pdbsum/6teo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6teo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SN114_YEAST SN114_YEAST]] Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP. [[http://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST]] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Absmeier, E]]
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[[Category: Ganichkin, O]]
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[[Category: Jia, J]]
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[[Category: Loll, B]]
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[[Category: Wahl, M C]]
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[[Category: Gtp]]
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[[Category: Snu114-prp8]]
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[[Category: Splicing]]

Revision as of 09:54, 18 March 2020

Crystal structure of a yeast Snu114-Prp8 complex

PDB ID 6teo

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