5u6e

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Current revision (13:21, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5u6e' size='340' side='right'caption='[[5u6e]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='5u6e' size='340' side='right'caption='[[5u6e]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5u6e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U6E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U6E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5u6e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U6E FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=82M:N-{(1S)-2-AMINO-1-[5-(HYDROXYMETHYL)-4-METHYL-1,3-THIAZOL-2-YL]ETHYL}-5-(4-CHLORO-3-FLUOROPHENYL)-1H-PYRROLE-2-CARBOXAMIDE'>82M</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.095&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HIV-1 Env ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=82M:N-{(1S)-2-AMINO-1-[5-(HYDROXYMETHYL)-4-METHYL-1,3-THIAZOL-2-YL]ETHYL}-5-(4-CHLORO-3-FLUOROPHENYL)-1H-PYRROLE-2-CARBOXAMIDE'>82M</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u6e OCA], [http://pdbe.org/5u6e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u6e RCSB], [http://www.ebi.ac.uk/pdbsum/5u6e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u6e ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u6e OCA], [https://pdbe.org/5u6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u6e RCSB], [https://www.ebi.ac.uk/pdbsum/5u6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u6e ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0M3KKW9_9HIV1 A0A0M3KKW9_9HIV1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Debnath, A K]]
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[[Category: Debnath AK]]
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[[Category: Kwon, Y D]]
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[[Category: Kwon YD]]
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[[Category: Kwong, P D]]
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[[Category: Kwong PD]]
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[[Category: Hiv-1]]
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[[Category: Nbd-14010]]
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[[Category: Small molecule]]
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[[Category: Viral protein]]
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[[Category: Virus entry antagonist]]
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Current revision

Crystal structure of clade A/E HIV-1 gp120 core in complex with NBD-14010

PDB ID 5u6e

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