5umv

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Current revision (13:30, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5umv' size='340' side='right'caption='[[5umv]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='5umv' size='340' side='right'caption='[[5umv]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5umv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UMV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5umv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UMV FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">REV1, YOR346W, O6339 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5umv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5umv OCA], [http://pdbe.org/5umv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5umv RCSB], [http://www.ebi.ac.uk/pdbsum/5umv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5umv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5umv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5umv OCA], [https://pdbe.org/5umv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5umv RCSB], [https://www.ebi.ac.uk/pdbsum/5umv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5umv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/REV1_YEAST REV1_YEAST]] Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.<ref>PMID:8751446</ref> <ref>PMID:11316789</ref> <ref>PMID:16452144</ref>
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[https://www.uniprot.org/uniprot/REV1_YEAST REV1_YEAST] Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.<ref>PMID:8751446</ref> <ref>PMID:11316789</ref> <ref>PMID:16452144</ref>
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Botuyan, M V]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Lee, J]]
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[[Category: Botuyan MV]]
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[[Category: Mer, G]]
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[[Category: Lee J]]
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[[Category: Thompson, J R]]
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[[Category: Mer G]]
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[[Category: Xu, C]]
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[[Category: Thompson JR]]
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[[Category: Brct domain]]
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[[Category: Xu C]]
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[[Category: Dna damage bypass]]
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[[Category: Pcna]]
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[[Category: Rev1]]
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[[Category: Transcription]]
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[[Category: Translesion dna synthesis]]
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Current revision

Crystal structure of the BRCT domain of S. cerevisiae Rev1

PDB ID 5umv

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