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6pey

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Current revision (07:27, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6pey' size='340' side='right'caption='[[6pey]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
<StructureSection load='6pey' size='340' side='right'caption='[[6pey]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6pey]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PEY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PEY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6pey]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PEY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.88&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylenetetrahydrofolate_reductase_(NAD(P)H) Methylenetetrahydrofolate reductase (NAD(P)H)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.20 1.5.1.20] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pey OCA], [http://pdbe.org/6pey PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pey RCSB], [http://www.ebi.ac.uk/pdbsum/6pey PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pey ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pey OCA], [https://pdbe.org/6pey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pey RCSB], [https://www.ebi.ac.uk/pdbsum/6pey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pey ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/METF_ECOLI METF_ECOLI] Methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine.<ref>PMID:14275142</ref>
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==See Also==
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*[[Methylenetetrahydrofolate reductase 3D structures|Methylenetetrahydrofolate reductase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bolen, R L]]
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[[Category: Bolen RL]]
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[[Category: Collins, K]]
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[[Category: Collins K]]
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[[Category: Frasco, F G]]
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[[Category: Frasco FG]]
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[[Category: Gallagher, E L]]
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[[Category: Gallagher EL]]
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[[Category: Garland, E]]
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[[Category: Garland E]]
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[[Category: Gurney, L A]]
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[[Category: Gurney LA]]
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[[Category: Halloran, J]]
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[[Category: Halloran J]]
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[[Category: Handley-Pendelton, J]]
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[[Category: Handley-Pendelton J]]
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[[Category: Hernandez, V]]
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[[Category: Hernandez V]]
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[[Category: Leffler, S]]
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[[Category: Leffler S]]
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[[Category: Perez, A]]
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[[Category: Perez A]]
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[[Category: Soares, A]]
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[[Category: Soares A]]
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[[Category: Stojanoff, V]]
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[[Category: Stojanoff V]]
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[[Category: Trimmer, E]]
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[[Category: Trimmer E]]
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[[Category: Williams, D]]
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[[Category: Williams D]]
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[[Category: Methyltransferase]]
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[[Category: Oxidoreductase]]
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[[Category: Reductase]]
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Current revision

MTHFR with mutation Asp120Ala

PDB ID 6pey

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