1a1q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1a1q.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1a1q.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1a1q| PDB=1a1q | SCENE= }}
{{STRUCTURE_1a1q| PDB=1a1q | SCENE= }}
-
'''HEPATITIS C VIRUS NS3 PROTEINASE'''
+
===HEPATITIS C VIRUS NS3 PROTEINASE===
-
==Overview==
+
<!--
-
During replication of hepatitis C virus (HCV), the final steps of polyprotein processing are performed by a viral proteinase located in the N-terminal one-third of nonstructural protein 3. The structure of NS3 proteinase from HCV BK strain was determined by X-ray crystallography at 2.4 angstrom resolution. NS3P folds as a trypsin-like proteinase with two beta barrels and a catalytic triad of His-57, Asp-81, Ser-139. The structure has a substrate-binding site consistent with the cleavage specificity of the enzyme. Novel features include a structural zinc-binding site and a long N-terminus that interacts with neighboring molecules by binding to a hydrophobic surface patch.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8861916}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8861916 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8861916}}
==About this Structure==
==About this Structure==
Line 32: Line 36:
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Serine protease]]
[[Category: Serine protease]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 09:40:30 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 15:48:20 2008''

Revision as of 12:48, 30 June 2008

Image:1a1q.png

Template:STRUCTURE 1a1q

HEPATITIS C VIRUS NS3 PROTEINASE

Template:ABSTRACT PUBMED 8861916

About this Structure

1A1Q is a Single protein structure of sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site., Love RA, Parge HE, Wickersham JA, Hostomsky Z, Habuka N, Moomaw EW, Adachi T, Hostomska Z, Cell. 1996 Oct 18;87(2):331-42. PMID:8861916

Page seeded by OCA on Mon Jun 30 15:48:20 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1a1q"
Personal tools