1qqe

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<StructureSection load='1qqe' size='340' side='right'caption='[[1qqe]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='1qqe' size='340' side='right'caption='[[1qqe]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1qqe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QQE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1qqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QQE FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qqe OCA], [http://pdbe.org/1qqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qqe RCSB], [http://www.ebi.ac.uk/pdbsum/1qqe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qqe ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qqe OCA], [https://pdbe.org/1qqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qqe RCSB], [https://www.ebi.ac.uk/pdbsum/1qqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qqe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SEC17_YEAST SEC17_YEAST]] SNARE complex protein that binds to cis-SNARE complexes on membranes and is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus and for homotypic vacuole fusion. During the priming step of membrane fusion, is released from cis-SNARE complexes by SEC18 to establish a pool of unpaired SNAREs, which are required for interactions in trans during docking and fusion steps. Can displace HOPS from SNARE complexes, which may be a prerequisite for trans-SNARE complex disassembly and subsequent rounds of priming, docking and fusion.<ref>PMID:8620540</ref> <ref>PMID:8670830</ref> <ref>PMID:9144293</ref> <ref>PMID:15889152</ref>
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[[https://www.uniprot.org/uniprot/SEC17_YEAST SEC17_YEAST]] SNARE complex protein that binds to cis-SNARE complexes on membranes and is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus and for homotypic vacuole fusion. During the priming step of membrane fusion, is released from cis-SNARE complexes by SEC18 to establish a pool of unpaired SNAREs, which are required for interactions in trans during docking and fusion steps. Can displace HOPS from SNARE complexes, which may be a prerequisite for trans-SNARE complex disassembly and subsequent rounds of priming, docking and fusion.<ref>PMID:8620540</ref> <ref>PMID:8670830</ref> <ref>PMID:9144293</ref> <ref>PMID:15889152</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 10:01, 15 September 2021

CRYSTAL STRUCTURE OF THE VESICULAR TRANSPORT PROTEIN SEC17

PDB ID 1qqe

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