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5we7

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Current revision (14:15, 13 March 2024) (edit) (undo)
 
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<StructureSection load='5we7' size='340' side='right'caption='[[5we7]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
<StructureSection load='5we7' size='340' side='right'caption='[[5we7]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5we7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/I09a0 I09a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WE7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5we7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/California/04/2009(H1N1)) Influenza A virus (A/California/04/2009(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WE7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G3K:2-{(2R)-1-[2-(4-chlorophenoxy)-2-methylpropanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic+acid'>G3K</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w3i|5w3i]], [[5w44|5w44]], [[5w73|5w73]], [[5w7u|5w7u]], [[5w92|5w92]], [[5w9g|5w9g]], [[5wa6|5wa6]], [[5wa7|5wa7]], [[5wap|5wap]], [[5wb3|5wb3]], [[5wdw|5wdw]], [[5wcs|5wcs]], [[5wct|5wct]], [[5wdn|5wdn]], [[5wdc|5wdc]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G3K:2-{(2R)-1-[2-(4-chlorophenoxy)-2-methylpropanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic+acid'>G3K</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=641501 I09A0])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5we7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5we7 OCA], [https://pdbe.org/5we7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5we7 RCSB], [https://www.ebi.ac.uk/pdbsum/5we7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5we7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5we7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5we7 OCA], [http://pdbe.org/5we7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5we7 RCSB], [http://www.ebi.ac.uk/pdbsum/5we7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5we7 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/C3W5S0_I09A0 C3W5S0_I09A0]
==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: I09a0]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kumar, G]]
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[[Category: Kumar G]]
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[[Category: White, S W]]
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[[Category: White SW]]
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[[Category: Cap-snatching]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Nuclease]]
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[[Category: Transcription]]
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[[Category: Virus]]
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Current revision

Crystal structure of the influenza virus PA endonuclease in complex with an inhibitor - SRI-29782

PDB ID 5we7

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