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2ctx
From Proteopedia
(Difference between revisions)
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<StructureSection load='2ctx' size='340' side='right'caption='[[2ctx]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2ctx' size='340' side='right'caption='[[2ctx]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ctx]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ctx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Indian_cobra Indian cobra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CTX FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ctx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ctx OCA], [https://pdbe.org/2ctx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ctx RCSB], [https://www.ebi.ac.uk/pdbsum/2ctx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ctx ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/NXL3_NAJNA NXL3_NAJNA]] Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (only alpha-7 alpha-8 alpha-9) nicotinic acetylcholine receptors (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 20:37, 20 October 2021
THE REFINED CRYSTAL STRUCTURE OF ALPHA-COBRATOXIN FROM NAJA NAJA SIAMENSIS AT 2.4-ANGSTROMS RESOLUTION
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