1qqh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='1qqh' size='340' side='right'caption='[[1qqh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1qqh' size='340' side='right'caption='[[1qqh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1qqh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpv18 Hpv18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QQH FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1qqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hpv18 Hpv18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QQH FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qqh OCA], [http://pdbe.org/1qqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qqh RCSB], [http://www.ebi.ac.uk/pdbsum/1qqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qqh ProSAT]</span></td></tr>
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qqh OCA], [https://pdbe.org/1qqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qqh RCSB], [https://www.ebi.ac.uk/pdbsum/1qqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qqh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/VE2_HPV18 VE2_HPV18]] E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.
+
[[https://www.uniprot.org/uniprot/VE2_HPV18 VE2_HPV18]] E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 27: Line 27:
</div>
</div>
<div class="pdbe-citations 1qqh" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1qqh" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Regulatory protein E2|Regulatory protein E2]]
== References ==
== References ==
<references/>
<references/>

Revision as of 07:18, 22 September 2021

2.1 A CRYSTAL STRUCTURE OF THE HUMAN PAPILLOMAVIRUS TYPE 18 E2 ACTIVATION DOMAIN

PDB ID 1qqh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qqh"
Personal tools