6uuz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6uuz is ON HOLD
+
==Structure of ACLY in the presence of citrate and CoA==
-
 
+
<StructureSection load='6uuz' size='340' side='right'caption='[[6uuz]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-
Authors: Xuepeng, W., Ronen, M.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6uuz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UUZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UUZ FirstGlance]. <br>
-
Description: Structure of ACLY in the presence of citrate and CoA
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP_citrate_synthase ATP citrate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.8 2.3.3.8] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uuz OCA], [http://pdbe.org/6uuz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uuz RCSB], [http://www.ebi.ac.uk/pdbsum/6uuz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uuz ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/ACLY_HUMAN ACLY_HUMAN]] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.<ref>PMID:23932781</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: ATP citrate synthase]]
 +
[[Category: Large Structures]]
 +
[[Category: Ronen, M]]
[[Category: Xuepeng, W]]
[[Category: Xuepeng, W]]
-
[[Category: Ronen, M]]
+
[[Category: Enzyme]]
 +
[[Category: Lyase]]

Revision as of 08:29, 1 January 2020

Structure of ACLY in the presence of citrate and CoA

PDB ID 6uuz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools