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4ttv

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<StructureSection load='4ttv' size='340' side='right'caption='[[4ttv]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='4ttv' size='340' side='right'caption='[[4ttv]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ttv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TTV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ttv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TTV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BC9:(1R,2R)-2-[(2S,6E,8R,9S,11R,13S,15S,16S)-7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADEC-6-EN-2-YL]CYCLOBUTANECARBOXYLIC+ACID'>BC9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BC9:(1R,2R)-2-[(2S,6E,8R,9S,11R,13S,15S,16S)-7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADEC-6-EN-2-YL]CYCLOBUTANECARBOXYLIC+ACID'>BC9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TARS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ttv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ttv OCA], [https://pdbe.org/4ttv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ttv RCSB], [https://www.ebi.ac.uk/pdbsum/4ttv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ttv ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine--tRNA_ligase Threonine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.3 6.1.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ttv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ttv OCA], [http://pdbe.org/4ttv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ttv RCSB], [http://www.ebi.ac.uk/pdbsum/4ttv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ttv ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYTC_HUMAN SYTC_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Threonine--tRNA ligase]]
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[[Category: Fang P]]
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[[Category: Fang, P]]
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[[Category: Guo M]]
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[[Category: Guo, M]]
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[[Category: Inhibitor]]
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[[Category: Ligase-antibiotic complex]]
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[[Category: Macrolide]]
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[[Category: Synthetase]]
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[[Category: Trna]]
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Revision as of 10:55, 15 March 2023

Crystal structure of human ThrRS complexing with a bioengineered macrolide BC194

PDB ID 4ttv

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