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4wrd

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<StructureSection load='4wrd' size='340' side='right'caption='[[4wrd]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4wrd' size='340' side='right'caption='[[4wrd]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wrd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WRD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wrd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WRD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc, SACOL0860 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrd OCA], [https://pdbe.org/4wrd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wrd RCSB], [https://www.ebi.ac.uk/pdbsum/4wrd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wrd ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrd OCA], [http://pdbe.org/4wrd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wrd RCSB], [http://www.ebi.ac.uk/pdbsum/4wrd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wrd ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NUC_STAAC NUC_STAAC]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
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[https://www.uniprot.org/uniprot/NUC_STAAC NUC_STAAC] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
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==See Also==
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*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Micrococcal nuclease]]
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[[Category: Staphylococcus aureus subsp. aureus COL]]
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[[Category: Staac]]
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[[Category: Bell-Upp PC]]
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[[Category: Bell-Upp, P C]]
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[[Category: Garcia-Moreno E B]]
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[[Category: E., B Garcia-Moreno]]
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[[Category: Schlessman JL]]
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[[Category: Schlessman, J L]]
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[[Category: Hydrolase]]
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[[Category: Internal ionizable group]]
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[[Category: Nuclease]]
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[[Category: Pdtp]]
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[[Category: Ph-sensitive switch]]
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Revision as of 07:21, 7 April 2023

Crystal structure of Staphylcoccal nulease variant Delta+PHS V66E L125E at cryogenic temperature

PDB ID 4wrd

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