5i0a

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Current revision (08:19, 23 August 2023) (edit) (undo)
 
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<StructureSection load='5i0a' size='340' side='right'caption='[[5i0a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='5i0a' size='340' side='right'caption='[[5i0a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5i0a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I0A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5i0a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I0A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TCE:3,3,3-PHOSPHANETRIYLTRIPROPANOIC+ACID'>TCE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i0a OCA], [http://pdbe.org/5i0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i0a RCSB], [http://www.ebi.ac.uk/pdbsum/5i0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i0a ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TCE:3,3,3-PHOSPHANETRIYLTRIPROPANOIC+ACID'>TCE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i0a OCA], [https://pdbe.org/5i0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i0a RCSB], [https://www.ebi.ac.uk/pdbsum/5i0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i0a ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RECA_MYCTU RECA_MYCTU] Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.[HAMAP-Rule:MF_00268] PI-MtuI is an endonuclease.[HAMAP-Rule:MF_00268]
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__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Li, H M]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Li, Z]]
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[[Category: Li HM]]
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[[Category: Zhang, J]]
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[[Category: Li Z]]
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[[Category: Cisplatin]]
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[[Category: Zhang J]]
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[[Category: Inhibitor]]
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[[Category: Intein]]
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[[Category: Splicing]]
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Current revision

RecA mini intein in complex with cisplatin

PDB ID 5i0a

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