1ubq

From Proteopedia

(Difference between revisions)

Revision as of 09:39, 29 September 2021

STRUCTURE OF UBIQUITIN REFINED AT 1.8 ANGSTROMS RESOLUTION

Structural highlights

1ubq is a 1 chain structure with sequence from Human. The December 2004 RCSB PDB Molecule of the Month feature on Ubiquitin by David S. Goodsell is 10.2210/rcsb_pdb/mom_2004_12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The crystal structure of human erythrocytic ubiquitin has been refined at 1.8 A resolution using a restrained least-squares procedure. The crystallographic R-factor for the final model is 0.176. Bond lengths and bond angles in the molecule have root-mean-square deviations from ideal values of 0.016 A and 1.5 degrees, respectively. A total of 58 water molecules per molecule of ubiquitin are included in the final model. The last four residues in the molecule appear to have partial occupancy or large thermal motion. The overall structure of ubiquitin is extremely compact and tightly hydrogen-bonded; approximately 87% of the polypeptide chain is involved in hydrogen-bonded secondary structure. Prominent secondary structural features include three and one-half turns of alpha-helix, a short piece of 3(10)-helix, a mixed beta-sheet that contains five strands, and seven reverse turns. There is a marked hydrophobic core formed between the beta-sheet and alpha-helix. The molecule features a number of unusual secondary structural features, including a parallel G1 beta-bulge, two reverse Asx turns, and a symmetrical hydrogen-bonding region that involves the two helices and two of the reverse turns.

Structure of ubiquitin refined at 1.8 A resolution.,Vijay-Kumar S, Bugg CE, Cook WJ J Mol Biol. 1987 Apr 5;194(3):531-44. PMID:3041007^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Vijay-Kumar S, Bugg CE, Cook WJ. Structure of ubiquitin refined at 1.8 A resolution. J Mol Biol. 1987 Apr 5;194(3):531-44. PMID:3041007

1 Structural highlights
2 Evolutionary Conservation
3 Publication Abstract from PubMed
4 See Also
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ubq"

@@ Line 3: / Line 3: @@
 <StructureSection load='1ubq' size='340' side='right'caption='[[1ubq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1ubq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. The December 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Ubiquitin''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2004_12 10.2210/rcsb_pdb/mom_2004_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UBQ FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1ubq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. The December 2004 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Ubiquitin''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2004_12 10.2210/rcsb_pdb/mom_2004_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UBQ FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ubq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ubq OCA], [http://pdbe.org/1ubq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ubq RCSB], [http://www.ebi.ac.uk/pdbsum/1ubq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ubq ProSAT]</span></td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ubq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ubq OCA], [https://pdbe.org/1ubq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ubq RCSB], [https://www.ebi.ac.uk/pdbsum/1ubq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ubq ProSAT]</span></td></tr>
 </table>
 == Evolutionary Conservation ==
@@ Line 27: / Line 27: @@
 ==See Also==
-*[[Ubiquitin|Ubiquitin]]
+*[[3D structures of ubiquitin|3D structures of ubiquitin]]
 == References ==
 <references/>

1ubq

From Proteopedia

Revision as of 09:39, 29 September 2021

STRUCTURE OF UBIQUITIN REFINED AT 1.8 ANGSTROMS RESOLUTION

Structural highlights

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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