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5bne

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<StructureSection load='5bne' size='340' side='right'caption='[[5bne]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='5bne' size='340' side='right'caption='[[5bne]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5bne]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BNE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5bne]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BNE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P3:2-[(2-CARBOXYPHENYL)AMINO]-5-[(5-PHOSPHONOPENTYL)OXY]BENZOIC+ACID'>7P3</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P3:2-[(2-CARBOXYPHENYL)AMINO]-5-[(5-PHOSPHONOPENTYL)OXY]BENZOIC+ACID'>7P3</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qr9|3qr9]], [[4ij1|4ij1]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bne OCA], [https://pdbe.org/5bne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bne RCSB], [https://www.ebi.ac.uk/pdbsum/5bne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bne ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpD, Rv2192c, MTCY190.03c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bne OCA], [http://pdbe.org/5bne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bne RCSB], [http://www.ebi.ac.uk/pdbsum/5bne PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bne ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRPD_MYCTU TRPD_MYCTU]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anthranilate phosphoribosyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Baker, E N]]
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[[Category: Baker EN]]
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[[Category: Evans, G L]]
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[[Category: Evans GL]]
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[[Category: Lott, J S]]
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[[Category: Lott JS]]
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[[Category: Structural genomic]]
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[[Category: Anprt]]
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[[Category: Complex]]
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[[Category: Inhibitor]]
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[[Category: Lobenzarit-like analogue]]
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[[Category: Magnesium binding]]
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[[Category: Phosphoribosylpyrophosphate]]
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[[Category: Phosphoribosyltransferase]]
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[[Category: Prpp]]
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[[Category: Tbsgc]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Trpd]]
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Revision as of 06:00, 7 June 2023

Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

PDB ID 5bne

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