This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5v6r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:42, 4 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5v6r' size='340' side='right'caption='[[5v6r]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='5v6r' size='340' side='right'caption='[[5v6r]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5v6r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V6R FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5v6r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V6R FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5v6b|5v6b]], [[5v6e|5v6e]], [[5v6h|5v6h]], [[5v6t|5v6t]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Plxnd1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6r OCA], [https://pdbe.org/5v6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v6r RCSB], [https://www.ebi.ac.uk/pdbsum/5v6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6r ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6r OCA], [http://pdbe.org/5v6r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v6r RCSB], [http://www.ebi.ac.uk/pdbsum/5v6r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6r ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PLXD1_MOUSE PLXD1_MOUSE]] Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Mediates anti-angiogenic signaling in response to SEMA3E. Required for normal development of the heart and vasculature.<ref>PMID:15239958</ref> <ref>PMID:17318185</ref> <ref>PMID:18992737</ref> <ref>PMID:19027330</ref> <ref>PMID:19421194</ref> <ref>PMID:22179111</ref>
+
[https://www.uniprot.org/uniprot/PLXD1_MOUSE PLXD1_MOUSE] Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Mediates anti-angiogenic signaling in response to SEMA3E. Required for normal development of the heart and vasculature.<ref>PMID:15239958</ref> <ref>PMID:17318185</ref> <ref>PMID:18992737</ref> <ref>PMID:19027330</ref> <ref>PMID:19421194</ref> <ref>PMID:22179111</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 20:
==See Also==
==See Also==
-
*[[Plexin|Plexin]]
+
*[[Plexin 3D structures|Plexin 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 27: Line 26:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Mus musculus]]
-
[[Category: Shang, G]]
+
[[Category: Shang G]]
-
[[Category: Zhang, X]]
+
[[Category: Zhang X]]
-
[[Category: Protein binding]]
+
-
[[Category: Rap gap]]
+

Current revision

Structure of Plexin D1 intracellular domain

PDB ID 5v6r

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools